Our Mission
We envision a world in which there is free and unrestricted access to information on malaria, independent of geographical locality or socio-economic status. No matter who you are, where you are, or what you do, access to information is the key to knowledge.
Knowledge empowers. Empowered people prevent and control malaria better.
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Although the future climate in the UK is favourable for the transmission of vivax malaria, the future risk of locally transmitted malaria is considered low because of low vector biting rates and the low probability of vectors feeding on a malaria-infected person.
The data collated here are published alongside this paper where it may help guide future sampling location decisions, help with the planning of vector control suites nationally and encourage broader research inquiry into vector species niche modelling.
Anti-malarial policy changes in neighbouring countries may have had an impact on the prevalence of molecular markers of anti-malarial resistance in Swaziland, and it is hoped that this new information will add to understanding of the regional anti-malarial resistance map.
This study provides a comprehensive overview of olfactory coding mechanisms of An. gambiae that ultimately may aid in fostering the design and development of olfactory-based strategies for reducing the transmission of malaria and other mosquito-borne diseases.
The scope of this review is the prevention of Plasmodium falciparum, which is the malaria species that causes the overwhelming majority of severe disease and death, and which in many areas of the world is frequently resistant to the classical antimalarial agent chloroquine.
In this study we determined the function of PfPuf2, a member of the Puf family of translational repressors, in gametocytogenesis of Plasmodium falciparum.
ATM, mutated in ataxia telangiectasia, is critical for the genotoxic stress response and its deficiency is associated with accelerated atherosclerosis and insulin resistance in humans and mice. The anti-malarial drug chloroquine activates ATM signaling and improves metabolic phenotypes in mice.
Together, our results indicate the presence of multiple mechanisms of gene regulation in the parasite.
