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Free Book for MalariaWorld Members!

November 27, 2012 - 21:45 -- Bart G.J. Knols

This week I was contacted by Dr. Dana Dalrymple with a very unusual offer. He wishes to provide all MalariaWorld subscribers free access to his book 'Artemisia annua, Artemisinin, ACTs & Malaria Control in Africa' published just seven months ago. This is truly remarkable and we highly appreciate this gesture!

In his email he said: "This will get it to the heart of the international malaria community and doubtless reach many who otherwise may not have heard of, or had access to, it." That is the spirit of truly open and global collaboration we aim to achieve with MalariaWorld. So a big 'Thank you' to Dr. Dalrymple! If you download it, why not send him a private message through the platform (available to subcribers) to let him know you appreciate his action...

The key ingredient in the most effective treatments for malaria in Africa - artemisinin - comes not from high-tech research, but is an extract of an ancient Chinese medicinal plant, Artemisia annua, commonly known as Artemisia. Chloroquine and replacement drugs have lost effectiveness with the development of resistance and have increasingly been replaced by derivatives of artemisinin combined with other drugs. Known as artemisinin–based combination therapies (ACTs), they provide the most effective treatment at present. This has led to efforts to increase cultivated production of Artemisia in the short run and to develop, through biological and chemical research, synthetic substitutes in the longer run.
The resulting interplay provides both opportunities and challenges for society. While individual components have been examined, there is little in the way of comprehensive analysis. This paper attempts to weave the many complex and dynamic components - historical, scientific, technical, and economic - together in order to aid understanding of the issues and facilitate development of informed public/private policies and actions. Although focused on Africa, the main components and issues are global in nature and resolution and relate to more general issues in infectious disease control and economic development.
 
Dana G. Dalrymple is an agricultural economist by vocation and a historian by avocation. He spent most of his career with the U.S. government in international agricultural development and research, first with the Dept. of Agriculture (USDA) and then on detail to the Agency for Intl. Development (USAID). He received B.S. and M.S. degrees in pomology (horticulture) and agricultural economics from Cornell University, and a Ph.D. in the latter from Michigan State University.
 
The full book is attached to this blog - enjoy it, it is important material!
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Full Book - Artemisia annua3.03 MB
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Comments

Submitted by Steve (not verified) on

I just downloaded the book, and immediately ran into an apparent typo on page 1: "Due to control efforts, in part reviewed herein, deaths due to malaria have since declined; of the estimated global total of 665,000 in 2010, about 174 million or still 91% were in Africa." Was there a missing sentence about the number of INFECTIONS as opposed to deaths, which included the 174 million figure? Or did you mean 174,000?

Submitted by Dana Dalrymple on

Steve is, alas, quite right in noting an apparent numerical error in the second to last line from the bottom of p. 1. It should read "about 596 million or 91% were in Africa (WHO, 2011, ix). Within Africa," Thanks to him for catching this.