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Malaria eradication: Lessons from Israel and a tribute to Prof. Israel Kligler

April 13, 2014 - 17:49 -- J20 Jerusalem Conf
“Why has the Anti-Malarial work in Palestine been so successful?”
 
In 1925, the Malaria Commission of the League of Nations, after visiting Palestine, posed this question to itself. To which their written reply in 1925 was:
 
“In the first place, because evidence was available to prove that it was so. That is principally due to the thorough anti-malarial survey carried out everywhere before the work begun.”

Treatments in remote areas urgent to meet Millennium Development Goals

April 11, 2014 - 15:34 -- Debora Miranda

Integrated Community Case Management (iCCM) is a strategy that enables those living beyond the reach of health facilities to access lifesaving treatments. It should be a national priority and an integral part of national health sector plans, a recent symposium in Ghana has concluded.

New: MESA operational research grants start activities

April 10, 2014 - 22:15 -- MESA Alliance

New operational research projects in malaria elimination will start this April, after being selected for funding through MESA. The MESA operational research portfolio includes: proof-of-concept of novel vector control and diagnostic tools, use of mapping technologies for surveillance and tailored response, and mobile phone applications for hard to reach populations. Urban, rural and forest settings are addressed. The projects are summarised here.

Last week at MalariaWorld: MalariaWorld has been a free service for 5 years. Would you be willing to pay 10 USD per year for it? Let us know.

April 10, 2014 - 21:35 -- Bart G.J. Knols
Please help us by answering the following question in our latest Poll: MalariaWorld has been a free service for 5 years. Would you be willing to pay 10 USD per year for it? It is very important for us to receive your opinion. Just take a second and respond to this Poll. You will need to log-in to be able to respond (see information below if you don't know how) and you will find the Poll on the home page at www.malariaworld.org, scroll down on the left side. If you need assistance, just send an email to info@malariaworld.org.
 
PSI has got a vacancy for a deputy director at their malaria & child survival department in Washington DC, USA. Read the PSI malaria vacancy here. Feel free to share the vacancy with your fellow collegues.
 
News from MESA: New operational research projects in malaria elimination will start this April, after being selected for funding through MESA. Read MESA operational research grants start activities here.
 
This week we share a new column with you. Alvaro Pemartin from Spain shares his story about how he, as a European emergency doctor, was confronted with his ignorance about malaria when he faced the harsh reality in Sierra Leone. In a series of columns, Alvaro wants to reflect on the perception of malaria among western health professionals. Read his first column 'What do health professionals in Europe know about malaria? ‘Part I: European statistics’ here
 
Enjoy this week's MalariaWorld - the MW team.
 

Log in at MalariaWorld. Remember that you have to log-in at MW to read more, respond to polls, open attachments and get free copies of books and other documents. Forgot your username and/or password? Go to www.malariaworld.org, click on Sign in and then on Request new password. Fill out your email address that you use to receive the MW newsletter and the Word verification. You will then receive further instructions by email.
 
Interested in publishing in our (peer-reviewed) MalariaWorld Journal (free reading & free publishing)? Then read more here or contact us at mwj@malariaworld.org

Column: What do health professionals in Europe know about malaria? ‘Part I: European statistics’

April 10, 2014 - 20:00 -- Ingeborg van Schayk

Four years ago, after working for six years as a hospital and pre-hospital emergency doctor in Spain, I accepted a position as a remote site doctor in Sierra Leone. Until then malaria was an obscure, almost phantasmagorical, condition to me.

Open access Cochrane Reviews of malaria interventions

April 8, 2014 - 15:42 -- Dee Walshe

Hello,

Recently, we at the Cochrane Infectious Diseases Group (CIDG) have published several systematic reviews of malaria interventions which may be of interest to Malaria World members. Each of the reviews are open access and are listed below:

• Mass drug administration for malaria

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008846.pub2/abstract

• Larvivorous fish for preventing malaria transmission

Column: Where do you hang a mosquito net in the bush?

April 2, 2014 - 19:22 -- Bart G.J. Knols
So you live in DR Congo. Your youngest child has visited the health post today, she is diagnosed with malaria. You were lucky that there was somebody at the clinic today. They gave you a blister with drugs. It is not quite clear how you got the first capsule into this two year old, but you managed. She is asleep now, safely under a mosquito net that was donated to you last year.
 
All of a sudden you hear noise outside. Gunshots, men running, men screaming. You know what this means. You, your family, you have to run. NOW.
 

Column: Social values & beliefs: the key to successful malaria prevention?

March 23, 2014 - 08:46 -- Ingeborg van Schayk
Do social norms and cost sharing matter in obtaining community buy in and adding value to health commodities? An excerpt from the field with emphasis on community based participatory methods and insecticide treated bed net (ITN) usage.
 

Are in vitro antimalarial assays a waste of time?

March 22, 2014 - 08:59 -- Pierre Lutgen

by Patrick Engeu Ogwang and Pierre Lutgen

Most of the assessments on the antimalarial efficacy of a molecule are made in vitro. In the case of plant material the first step is generally the extraction with an organic solvent. The extract is then lyophilized, frozen and stored for subsequent trials.

Malaria testing not a simple fix in the private sector

March 21, 2014 - 12:22 -- Debora Miranda

Drug shops offering quick diagnostic tests for malaria can improve treatment, but regulation by authorities is also needed, researchers warn.

Read the story and the article at: http://www.actconsortium.org/news.php/66/malaria-testing-not-a-simple-fix-in-the-private-sector

Malaria rapid diagnostic tests (RDTs) are simple tools to diagnose malaria accurately and can help health workers in remote locations to prescribe the correct treatment. But introducing RDTs into the private sector may have complex, unexpected consequences for patients.

Malaria testing not a simple fix in the private sector

March 21, 2014 - 12:21 -- Debora Miranda

Drug shops offering quick diagnostic tests for malaria can improve treatment, but regulation by authorities is also needed, researchers warn.

Read the story and the article at: http://www.actconsortium.org/news.php/66/malaria-testing-not-a-simple-fix-in-the-private-sector

Malaria rapid diagnostic tests (RDTs) are simple tools to diagnose malaria accurately and can help health workers in remote locations to prescribe the correct treatment. But introducing RDTs into the private sector may have complex, unexpected consequences for patients.

Last week at MalariaWorld: Sad news & more...

March 21, 2014 - 11:25 -- Last week at Ma...
With great sadness we have to inform you that on the 16th of March Ernst-Jan Scholte, 40 yrs, passed away. With E.J. we lose a dear colleague who was a pioneer in the use of entomopathogenic fungi for the control of mosquitoes. We have come to know E.J. as a passionate professional, a talented guitar player and a very gentle person. E.J. once was one of Bart’s students and stayed for some months with Bart and Inga during his internship in Kenya in 1998. Read Bart’s personal story about E.J. here. 
 
We wish his wife, Patrizia, and his two children, Sofia and Stefano, all the strength they need.

Do you see patients with cerebral malaria? ...Or know someone who does?

March 21, 2014 - 11:16 -- Lakshmi Swamy

If you care for patients with cerebral malaria or know someone who does, then we would appreciate your help in distributing this short survey.
Please use the following link to complete the survey: Cerebral Malaria Diagnosis Survey

I am an ophthalmologist with a background in malaria biology, and I am leading a survey study to understand how clinicians diagnose cerebral malaria.

In memoriam: Ernst-Jan Scholte (1974 - 2014)

March 20, 2014 - 19:00 -- Bart G.J. Knols

It is with great sadness that I report the passing of my friend, colleague and my former PhD student Dr. Ernst-Jan Scholte, yesterday, 16 March 2014. Although obituaries are normally written for scientists that died at an old age and had a massive track record in our field, I feel the urge to commemorate and remember this great person in front of you all at MalariaWorld. He became only 40 years of age - after fighting cancer for a year.

Ernst-Jan first contacted me in 1998 when he was still a biology student at the Wageningen University. At that time I was working in Nairobi for the International Centre of Insect Physiology and Ecology (ICIPE). Ernst-Jan (or EJ as many called him) wanted to study mosquitoes and do an internship with me for six months. He was lucky. Within a week after he arrived in Kenya we undertook a wonderful safari to the border with Tanzania, visiting and hiking in a Masai area where I had previously worked on tsetse flies. EJ loved it from day one. He fell in love with Africa, its people and its wildlife, and was extremely motivated in his work. I will never forget the nights we camped out in the bush together...

New: Book on architecture and health (notably malaria)

March 20, 2014 - 18:14 -- Bart G.J. Knols
Early nomadic shelters, including caves, animal skin tents, and igloos, were used for protection against the wind, rain, snow, sunlight, and other forces of nature. These basic homes also provided defence against predators and were used to store a few important possessions. They were temporary, and proximity to a water source was of prime importance.
 

Free International Innovation publication with special focus on malaria

March 20, 2014 - 18:00 -- MESA Alliance

International Innovation, has recently published an edition called 'Parasites of poverty: how international research is tackling the global threat of tropical disease'. In this edition there is a special focus on malaria: 'break the life cycle stop the spread."

In search of a postdoc position

March 19, 2014 - 15:07 -- Roy Faiman

Hello colleagues!
I'll be finishing a one-year postdoc at Cornell university.
My work here focused on behavioral assays on Aedes albopictus to try and improve our understanding of visual cues that aid the gravid females in locating and selecting an oviposition site.
As of July 1st I will available to begin a new position.
My masters and PhD work (Alon Warburg's lab, The Hebrew University of Jerusalem) involved sand fly ecology and control and leishmaniasis transmission dynamics in an emerging focus. My publications are available on line.

Column: Out of sight, out of mind? How has imaging advanced our understanding of Plasmodium infected erythrocytes?

March 12, 2014 - 21:57 -- Bart G.J. Knols
Being a lab-based malaria researcher in a non-endemic country, I’ve been really interested by the columns that our colleagues ‘in the field’ have shared; looking at vector populations, elimination strategies and experiences of disease themselves. My perspectives of malaria are rather different however, and I hope to share more of a laboratory angle in my contributions to MalariaWorld this year. With that in mind, where better to start than the microscope and how most of us first come ‘face to face’ with Plasmodium spp? 
 
A bit of history
 
Much of our knowledge of Plasmodium parasites has come from the ability to visualize them (reviewed by [1]). The first description of the causative agents of malaria by Laveran in 1880 was made possible by 400x magnification of infected blood samples, and detected the pigment we now know as haemozoin. Since then the Giemsa stain, developed in 1904, has made it possible to differentiate between species, and remains the clinical gold standard to diagnose infection... 

Updated version of book freely available

March 5, 2014 - 11:51 -- Bart G.J. Knols

The freely available book titled "Artemisia annua,Artemisinin, ACTs & Malaria Control in Africa: Tradition, Science and Public Policy", has been updated by the author, Dana Dalrymple, and has been expanded with an Annex (Annex 7), titled: "The Early Role of Novartis in ACT Development" (pp. 189-192).

The book is attached to this blog. We are grateful to Dr. Dalrymple to make this updated version available for free to MalariaWorld subscribers.

The MW team.

Column: Problems on the Horizon

March 2, 2014 - 22:08 -- Bart G.J. Knols
As an avid observer of malaria transmission patterns, I am becoming worried about sustaining the advances that have developed over the past ten or so years. There is no doubt that the advent of insecticide treated bednets has provided a vehicle for various interested parties to exploit as a means of vector control, and this has happened in huge numbers. Tens of millions of LLINs have been delivered to various governments, NGOs and other interested parties, and this is still happening. But when it comes to monitoring the effects of this intervention, when it comes to careful evaluation of the programmes, there isn’t much to hear...

Can malaria be suppressed in the Congo River Basin without developing the Grand Inga Dam?

February 28, 2014 - 12:50 -- William Jobin

Greetings,

Despite real progress in much of Africa, the two big elephants left in the room are Nigeria and the Congo. Because of poor infrastructure, continuing civil war, and very unstable political conditions, it is hard to imagine how we can attack malaria in the Congo. Although the US PMI has added them to their list, we all know it will be a long time before anything significant can be organized there.

Organizing indoor spray programs or bednet distribution takes a stable MOH, and is difficult in the midst of civil war.

WHO really wants to end Malaria?

February 28, 2014 - 04:49 -- Satoko Noritake

It might be a primary mistake to employ chemicals to control Malaria, or it might be because of egoism in developed countries: people who want to sell their chemical products, who need money to operate their own institutions. I recently read a book “Neem can save the earth” written in Japanese. Neem extracts have a lot of possibility to be utilized in malaria control and agriculture.

World Health Day (7 April) about vector-borne diseases

February 24, 2014 - 19:50 -- Bart G.J. Knols

This year World Health Day has its focus on vector-borne diseases, including malaria. The World Health Organization has set specific goals for this day, and is asking the international community working on malaria and other vectors to pay special attention towards protection from vector-borne diseases.

Avez-vous travaillez avec le PMI en Afrique ? Have you worked with US Presidential Malaria Initiative for Africa?

February 21, 2014 - 13:00 -- William Jobin

Chers Confreres et Colleagues,

The US Presidential Malaria Initiative (PMI) began in 2005 in Angola. I helped start it, along with 2 other consultants for RTI the US contractor, and 3 malariologists from the Angolan Ministry of Health. Since then PMI has expanded to cover 21 countries in Africa. The contract passed from RTI to Abt Associates, and others.

If you do simple math, that means we have accumulated about 1,000 person years since then, in Africa, fighting malaria. What a tremendous resource! Are you one of those people?

The inherent waste in ephemeral methods such as bednets or indoor spraying, compared to the accumulating benefit of land reclamation

February 18, 2014 - 14:06 -- William Jobin

When Martinho Somandjinga, Manuel Lluberas, Joaquim Canelas and I started the US PMI in Angola in 2005, the excitement and pride of our accomplishments carried us along for the first couple of years. Sure we spent over two million dollars in one small province each year, but it seemed worth it.

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