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The years teach much that the days never knew. (Unknown source)

August 11, 2014 - 10:44 -- Anton Alexander

“The years teach much that the days never knew” (Unknown source)
It has been puzzling why the architect of the start of the first successful national malaria-eradication campaign anywhere in the world, Dr I Kligler, should have been forgotten, and his work, until recently, almost unknown.

Pedro Alonso to replace Rob Newman at GMP

August 1, 2014 - 12:37 -- Clive Shiff

I am pleased to see that Pedro will take over the hard task that Rob Newman left. Rob was instrumental in bringing the Global Malaria Programme back to life, and now I would like to see it expand its influence. When one looks at the various malaria control operations in various countries and read the various blogs etc, it is apparent that there is a lack of coordination, and in most instances there are several agencies, donors, major players and national personalities operating.

YouTube film Science to accelerate us to malaria eradication

July 17, 2014 - 19:30 -- MESA Alliance
A great new science lecture is available on the MESA YouTube channel: 'Science to accelerate us to malaria eradication',  presented by Lee Hall at the Keystone Symposium 2014.
 
Lee presents some key concepts on the vibrant biomedical R&D agenda which we need to support progress towards global malaria eradication. In his lecture, he poses the question of how the changing epidemiology of malaria impacts on research and interventions and highlights five challenges:
 

Injectable artesunate: cure or killer?

June 27, 2014 - 13:16 -- Irene Teis

A document in Scientific American (June 2014) describes the activities of MVV Medecines for Malaria Ventures, a « non profit » organization (association sans but lucratif) located at Geneva. It is surprising to learn that they sell Artesunate in monotherapy for intravenous injection at high doses ; in cooperation with WHO and Médecins sans Frontières.

Review of 'what works' in elimination advocacy

June 19, 2014 - 18:55 -- MESA Alliance
Malaria Journal publishes an Open Access timely review of 'what works' in elimination advocacy. The authors identify 7 key advocacy elements for disease elimination:
 
  1. A global elimination plan, supported by international health bodies.
  2. Thorough costings and tools to support the business case.
  3. An approach that is positioned within a development framework.
  4. Core elimination advocacy messages.
  5. Provision of advocacy tools for partners.
  6. Extensive and effective community engagement.
  7. Strong partnerships

Prestigious NWO-Vidi grant to start a new malaria research group

June 3, 2014 - 11:37 -- Taco Kooij

Dear friends & colleagues,
I am extremely honoured, proud, and happy to announce that I have been awarded a prestigious Vidi grant from the Netherlands Organisation for Scientific Research (NWO) to start my own independent malaria research lab in Nijmegen. Below follows a press release providing further details.
Taco

Publication: Planning meeting for operational research on malaria elimination. WHO Meeting report May 2014

June 2, 2014 - 15:50 -- MESA Alliance

Number of pages: 9
Publication date: 2014
Languages: English
WHO reference number: WHO/HTM/ GMP/2014.5

Main objectives: reviewing the malaria operational research landscape; identifying operational challenges, bottlenecks and priority research questions in the transition from malaria control towards elimination; and reaching agreement among the meeting participants on the next steps, roles and responsibilities.

malaria and local blogging

May 31, 2014 - 19:33 -- Cliff Landesman

Why is there so little blogging about malaria from a local perspective? Those who live in regions of endemic malaria are not writing about it. As a result, it is hard to follow progress in combating malaria in a particular region. For example, I have an interest in malaria in western Kenya. However, it is difficult to know what programs are in place there, who is involved, what progress has been made. I am willing to bet that there is not a single blog anywhere where people living in an endemic region talk about malaria.

En Francais - Do you see patients with cerebral malaria? ...Or know someone who does?

May 30, 2014 - 01:34 -- Lakshmi Swamy

------------- Enquête sur le diagnostic du neuropaludisme--------------------
Nous sommes un groupe de médecins de l'université Duke aux États-Unis et de l'Université de Liverpool au Royaume-Uni. Notre objectif étant de mieux comprendre comment les médecins parviennent à poser un diagnostic de neuropaludisme, nous avons réalisé une enquête à ce sujet.

Need for some effective coordination in malaria control interventions

May 19, 2014 - 17:31 -- Clive Shiff

Wherever malaria has been eliminated, success was likely to have been based on the interplay of a series of mechanisms. In the United States it may have coincided with the advent of residual insecticides, but there were a variety of factors associated with the success. These were seasonal changes, environmental factors, political decisions that affected where people could live, the advent of improved treatments and increase in wealth and improvement of living standards. The same can be said of Italy and much of Europe in the early part of the 20th Century.

Milk, the forgotten antimalarial

May 19, 2014 - 13:30 -- Pierre Lutgen

It all begins in 1952 with the work of the Liverpool School of Tropical Medicine (BG Maegraith et al, British Medical Journal, 1952, 1382-3). They found that in rats inoculated with Plasmodium berghei and living on a diet of milk there was a strong suppression of the growth of the parasites. This was valid for retail whole cow’s milk, reconstituted dried milk from different origins and human milk. Most rats on normal laboratory diet died in a few days.

New publications from WHO GMP

May 13, 2014 - 08:30 -- MESA Alliance
Tags: 
Safety review of 8-aminoquinoline antimalarial medicines
 
Written by external authors, this document reviews published and unpublished studies about the safety of primaquine and its precursors, with particular attention to haemolytic anaemia in G6PD-deficient individuals. The study was prepared for and discussed at a 2012 meeting of the WHO evidence review group on the safety and effectiveness of single-dose primaquine as a P. falciparum gametocytocide.
 
Elimination scenario planning
 
WHO has published a manual to help malaria-endemic countries to assess the feasibility of moving towards elimination. The new guide provides a comprehensive framework to assess different scenarios and timelines for reducing the disease burden and moving towards elimination, depending on programme coverage and funding availability.

Artemisia sieberi and bicarbonate : a revolutionary mixture from Palestine

May 11, 2014 - 18:48 -- Pierre Lutgen

The mode of action of quinine and chloroquine is almost exclusively based on the inhibition of the crystallization of heme into hemozoin, killing plasmodium in its own digestive rejects. In several papers M Akkawi from the Al Quds University in Palestine has shown that extracts of several medicinal plants : Salvia officinalis, Artemisia sieberi, Artemisia afra, Artemisia annua, Inula viscosa had similar effects, in some cases equivalent or better than chloroquine for the inhibition of beta-hematin (see literature references below).

Launch of the MESA Alliance YouTube channel

May 6, 2014 - 09:33 -- MESA Alliance
Tags: 
The MESA Alliance YouTube Channel highlights great lectures, R&D, and lessons from malaria programmes from all over the malaria community. The channel adds another tool to MESA's function of highlighting great science from the community to the community. Browse the various playlists from 'Basic Science' to 'Eradication Strategies', and subscribe to the channel so you receive notifications when new content is posted.  Please send video suggestions to MESA@isglobal.org.

Rotary in support of Artemisia annua

May 3, 2014 - 17:33 -- Pierre Lutgen

In the April 2014 issue the magazine Rotary Contact from Belgium-Luxembourg duly recognized he efforts and results achieved by Rotarians from Ieper and Luxembourg in the promotion of Artemisia annua tea against malaria. Geert Flamang has launched plantations in Katanga and Pierre Lutgen has run clinical trials in several African countries which demonstrate an efficiency of >95%. These trials have allowed to show that the antimalarial potency can be increased by using the dried leaves in lieu of aqueous extracts, as powder in capsules or mixed with food.

A need for coordination of projects, donors and various players

May 2, 2014 - 13:17 -- Clive Shiff

I feel that we should start a conversation about coordination. I attended Malaria Day here in Baltimore last week, and one still hears people speaking as if all we have to do is send more nets to Africa! Africa is swimming in nets, in fact there are NO plans that one hears of to REPLACE (key word) expended of torn nets in anything but an ad hoc manner. Yet Anopheles funestus (resistant to pyrethoids) is appearing all over Eastern and Southern Africa.

World Malaria Day - Special Collection available from Cochrane Library

April 25, 2014 - 09:58 -- Dee Walshe

It is World Malaria Day today (Friday 25 April), and to help raise awareness there are two new Special Collections available from The Cochrane Library - one for malaria diagnosis and treatment, and one for prevention and control.

http://www.thecochranelibrary.com/details/collection/6117011/Malaria-dia...

OPEN ACCESS New Cochrane Review on malaria interventions

April 25, 2014 - 09:08 -- Dee Walshe

Hello,

A new open access Cochrane Review was released earlier this month by John Odaga et al. that may be of interest to Malaria World members:

Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008998.pub2/abstra...

Treatments in remote areas urgent to meet Millennium Development Goals

April 11, 2014 - 15:34 -- Debora Miranda

Integrated Community Case Management (iCCM) is a strategy that enables those living beyond the reach of health facilities to access lifesaving treatments. It should be a national priority and an integral part of national health sector plans, a recent symposium in Ghana has concluded.

New: MESA operational research grants start activities

April 10, 2014 - 22:15 -- MESA Alliance

New operational research projects in malaria elimination will start this April, after being selected for funding through MESA. The MESA operational research portfolio includes: proof-of-concept of novel vector control and diagnostic tools, use of mapping technologies for surveillance and tailored response, and mobile phone applications for hard to reach populations. Urban, rural and forest settings are addressed. The projects are summarised here.

Open access Cochrane Reviews of malaria interventions

April 8, 2014 - 15:42 -- Dee Walshe

Hello,

Recently, we at the Cochrane Infectious Diseases Group (CIDG) have published several systematic reviews of malaria interventions which may be of interest to Malaria World members. Each of the reviews are open access and are listed below:

• Mass drug administration for malaria

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008846.pub2/abstract

• Larvivorous fish for preventing malaria transmission

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