Over the past decades, Research and Development has played a key role in driving the achievements made against malaria with the development of tools such as rapid diagnostic tests (RDTs), artemisinin-combination therapies (ACTs) and long-lasting insecticide-treated nets (LLINs). We have also made great progress in our capacity to disseminate the scientific information to the malaria community; open access journals, webs, blogs, twitter, emails, conferences, publications, etc. However, one of the questions that remained pending was, “is it possible to track all current research projects focused on malaria elimination and eradication?”
Artemisia annua has strong allelopathic properties as was documented by Mediplant for the high artemisinin hybrid. In other words the plant becomes invasive and inhibits the growth of other plants or cash crop on fields where Artemisia has been planted for the extraction of artemisinin by Bigpharma.
With WHO's blessing Keasling's synthetic artemisinin replaces the natural product: an economical disaster for African families who have invested all their meager resources in Artemisia annua plantations, lured by the promise of big profits.
As this year is the centenary of the start of World War 1, perhaps readers may be interested to see how malaria may have changed the outcome of the war had the Turkish army managed to hang on after the last battle in 1918, as the British Army collapsed from malaria two weeks after that battle. See http://www.eradication-of-malaria.com/ww1-malaria.html This may be used to serve as a reminder to those who choose to ignore the disease and treat it casually.
MESA is very excited to be launching its new website and knowledge management tools at ASTMH in New Orleans on November 2nd!
Osana is a small, all natural anti mosquito soap. You simply wash with this bar of soap to keep mosqito away.
We are passionate about providing a non toxic solution to protect people naturally, as well as creating a sustainable product with no negative side effects.
Constant Tchandema and Pierre Lutgen
Potassium, the most abundant cation in the human body, regulates intracellular enzyme function and neuromuscular tissue excitability. Serum potassium is normally maintained within thenarrow range of 3.5 to 5.5 mEq/L.
Several recently published Cochrane Reviews from the Cochrane Infectious Diseases Group may of interest to Malaria World members:
Artemether for severe malaria (new review) http://ow.ly/CEOQi
Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment (updated review) http://ow.ly/CEPri
The Second Global Malaria Action Plan (GMAP2) will cover the timeframe 2016-2025.
You are strongly encouraged to have a look and contribute by sharing your vision for a malaria-free world.
A very important paper posted on www.malariaworld.org (Enabling factors facilitating the use of neem-based remedies for the management of malaria … ).
An apotheosis of herbal medicine
It documents in an excellent way the superiority of herbal medicine against malaria when compared with ACTs.
Clinical trials are not suitable to identify rare, potentially serious adverse effects of drugs, or to define their safety in high risk populations.
Artemisinin-based combination therapies (or ACTs) are considered safe, but there are concerns over their potential to cause damage to parts of the brain. There is also a concern about their safety in patients infected with HIV.
“The years teach much that the days never knew” (Unknown source)
Cambodia is moving towards eliminating malaria. According to the WHO World Malaria Report, less than 100 deaths were attributable to malaria in 2012 (World Malaria Report 2013).
In the 1970s, there were only about nine countries where dengue fever existed but now the number is closer to 60. As of 2010 dengue fever is believed to infect 50 to 100 million people worldwide per year with 1/2 million life-threatening infections There is no cure and no real treatment.
I am pleased to see that Pedro will take over the hard task that Rob Newman left. Rob was instrumental in bringing the Global Malaria Programme back to life, and now I would like to see it expand its influence. When one looks at the various malaria control operations in various countries and read the various blogs etc, it is apparent that there is a lack of coordination, and in most instances there are several agencies, donors, major players and national personalities operating.
About two years ago i met a friend who introduced me to the Bahai Faith, before then i had been a dormant Presbytarian. The ideals of the Bahai Faith have had so much impact in my life as a person. Anyhoo i came across this article, thought i would share it with you all.
At the 15th International Workshop on Clinical Pharmacology of HIV on May 19, 2014 at the University of Nebraska, FA Fehintola showed that nevirapine co-prescribed with artemether-lumefantrine may reduce the artemether concentration in blood by 70%.
A document in Scientific American (June 2014) describes the activities of MVV Medecines for Malaria Ventures, a « non profit » organization (association sans but lucratif) located at Geneva. It is surprising to learn that they sell Artesunate in monotherapy for intravenous injection at high doses ; in cooperation with WHO and Médecins sans Frontières.
- A global elimination plan, supported by international health bodies.
- Thorough costings and tools to support the business case.
- An approach that is positioned within a development framework.
- Core elimination advocacy messages.
- Provision of advocacy tools for partners.
- Extensive and effective community engagement.
- Strong partnerships
Dear friends & colleagues,
I am extremely honoured, proud, and happy to announce that I have been awarded a prestigious Vidi grant from the Netherlands Organisation for Scientific Research (NWO) to start my own independent malaria research lab in Nijmegen. Below follows a press release providing further details.
Why is there so little blogging about malaria from a local perspective? Those who live in regions of endemic malaria are not writing about it. As a result, it is hard to follow progress in combating malaria in a particular region. For example, I have an interest in malaria in western Kenya. However, it is difficult to know what programs are in place there, who is involved, what progress has been made. I am willing to bet that there is not a single blog anywhere where people living in an endemic region talk about malaria.
------------- Enquête sur le diagnostic du neuropaludisme--------------------
Nous sommes un groupe de médecins de l'université Duke aux États-Unis et de l'Université de Liverpool au Royaume-Uni. Notre objectif étant de mieux comprendre comment les médecins parviennent à poser un diagnostic de neuropaludisme, nous avons réalisé une enquête à ce sujet.
A group of French tourists, while crossing Africa by car, noticed that those drinking Artemisia annua tea where less attacked by the fierce mosquitoes of this continent than those relying on the standard pharmaceutical pills.
Wherever malaria has been eliminated, success was likely to have been based on the interplay of a series of mechanisms. In the United States it may have coincided with the advent of residual insecticides, but there were a variety of factors associated with the success. These were seasonal changes, environmental factors, political decisions that affected where people could live, the advent of improved treatments and increase in wealth and improvement of living standards. The same can be said of Italy and much of Europe in the early part of the 20th Century.
It all begins in 1952 with the work of the Liverpool School of Tropical Medicine (BG Maegraith et al, British Medical Journal, 1952, 1382-3). They found that in rats inoculated with Plasmodium berghei and living on a diet of milk there was a strong suppression of the growth of the parasites. This was valid for retail whole cow’s milk, reconstituted dried milk from different origins and human milk. Most rats on normal laboratory diet died in a few days.