Treatment

The analysis confirmed statistically-significant differences between the direct and indirect costs of treatment with and without chemoprophylaxis for patients with imported malaria.

RDT was cost effective in both low and high transmission settings.

In regions coendemic for P. vivax and P. falciparum, a unified treatment policy for malaria of any parasitological cause is likely to confer the greatest individual and public health benefit.

Four years after the withdrawal of CQ from national treatment guidelines the prevalence of the mutant pfcrt allele remains at 97%.

We present three cases of unusual and complicated malaria caused by Plasmodium vivax.

Community health workers can be trained to use RDTs and timers to assess and manage malaria and pneumonia in children.

Everybody used poor quality malaria treatment services but the poor people used providers with poor quality malaria treatment services more than others.

Although RDTs had low sensitivity and specificity, which varied widely depending on fever and parasite density, using RDTs reduced over-treatment with anti-malarials significantly.

The benzo[a]phenoxazine derivative, SSJ-183 has shown excellent anti-malarial efficacy and safety.

Pharmacological mechanism-based modeling was refined and used to develop an in silico model of antimalarial drug treatment validated against clinical and field data.