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The data highlight the complexity of the situation prevailing in southern Ghana and the challenges facing the malaria vector control programmes in this region.
We describe here a clinical failure in the treatment with mefloquine of acute falciparum malaria contracted in Africa and associated with in vitro mefloquine resistance and pfmdr1 copy number amplification.
This study is a necessary prerequisite to cartography malaria risk and to improve vector control operations in southern Benin.
Three cross-sectional surveys were also carried out. Malaria incidence showed a marked seasonal distribution with two peaks: the first corresponding to the long rainy season, and the second corresponding to the overflowing of Lake Nokoue.