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Detecting mutations in PfCRT and PfMDR1 genes among Plasmodium falciparum isolates from Saudi Arabia by pyrosequencing

Submitted by Kabogo on July 26, 2011 - 07:16
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Author(s): 
Saad M. Bin Dajem, Adel Ali H. Al-Sheikh, Marie Fe Bohol, Mohammad Alhawi, Mohammed N. Al-Ahdal & Ahmed Al-Qahtani
Reference: 
Parasitology Research, Volume 109, Number 2, 291-296
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Contact email: 
aqhatani@kfshrc.edu.sa

The emergence of chloroquine resistance in Plasmodium falciparum is a significant public health problem where malaria is endemic.

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In Vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease

Submitted by Kabogo on August 30, 2010 - 14:18
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Author(s): 
Essam Abdel-Sattar, Louis Maes and Maha Mahmoud Salama
Reference: 
Phytotherapy Research Volume 24, Issue 9, pages 1322–1328, September 2010
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Contact email: 
abdelsattar@yahoo.com

The in vitro activity of the methanol extracts of 51 plants randomly collected from the Kingdom of Saudi Arabia and some of their fractions (petroleum ether, chloroform, ethyl acetate and aqueous) were evaluated against Plasmodium falciparum, Trypanosoma brucei brucei, T. cruzi and Leishmania infantum, as well as toxicity against MRC-5 fibroblast cells.

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