Tanzania

PfEMP1 proteins comprise a family of variant antigens that appear on the surface of P. falciparum-infected erythrocytes and bind to multiple host receptors.

IPTi due to low coverage, late administration, drug resistance, decreased malaria transmission or improvements in vector control and case management.

PCR analyses from multiple blood samples collected during the early treatment phase revealed a complex picture of parasite sub-populations.

Asymptomatic, low density, multi-clone malaria infection was common in this study area.

This study points to several strategies that may help bridge the gap between what is known from research evidence and the knowledge and practices of healthcare providers.

The observed changes may be because of introduction of AL, and if so, this finding gives cause for concern and argues for continued surveillance of these molecular markers.

We found no evidence from this trial that zinc supplementation protected against malaria.

Here, we compare their concordance among 451 febrile episodes in a cohort of 2,058 children and adults followed over 6 months in a region in central Tanzania with hypoendemic malaria.

Malaria confirmation before treatment provides an opportunity for improving the quality of malaria case management in endemic regions.

These results add to the growing evidence of the decline in malaria associated with a decrease in non-typhoidal salmonellosis and possibly other bacteraemias.