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The resurgence of the malaria eradication agenda and the increasing number of severe manifestation reports has contributed to a renewed interested in the Plasmodium vivax infection.
Training of household heads on the utilization of LLITN significantly reduces the burden of malaria in under-five children.
The extent of CD55 loss from RBC of all ages early in the course of malarial anaemia and the correlation of CD55 with haemoglobin levels support the hypothesis that CD55 may play a causal role in this disorder.
The finding of conflicting reports about the exact role of these variants in severe disease underlies the complexity of the parasite–host interactions and highlights the need for further studies.
Flowcytometry was used to study expression of CR1, CD55 and CD59 in 50 Pf cases and 30 normal healthy volunteers.
By mapping the distribution of anaemia risk in preschool children adjusted for malnutrition and parasitic infections, we provide a means to identify the geographical limits of anaemia burden and the contribution that malnutrition and parasites make to anaemia.
More care should be taken to ensure proper nutrition and malaria prevention such as bed nets and intermittent preventive treatments to avoid these diseases and their effects on maternal and perinatal outcomes.
Scaling-up effective malaria interventions reduced malaria-related burden at health facilities by over 75% within 5 years.
The point estimate of the effect of IPTi on malaria is consistent with that from a large pooled analysis of randomized control trials.
While these additional analyses show a robust effect of vaccination on anaemia, this is an intensive exploration of secondary results and should, therefore, be interpreted with caution.