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Targeting glutathione by dimethylfumarate protects against experimental malaria by enhancing erythrocyte cell membrane scrambling

Submitted by Kabogo on July 19, 2010 - 12:44
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Author(s): 
M Ghashghaeinia, D Bobbala, T Wieder, S Koka, J ück, B Fehrenbacher, M Rocken, M Schaller, F Lang, K Ghoreschi
Reference: 
Am J Physiol Cell Physiol (July 14, 2010)
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Contact email: 
florian.lang@uni-tuebingen.de

The balance between GSH-levels and oxidative stress is critical for cell survival. The GSH-levels of erythrocytes are dramatically decreased during infection with Plasmodium spp.

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