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Open Access | Malaria: Origin of the Term ‘‘Hypnozoite’’

Submitted by Inga on November 24, 2011 - 11:13
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Author(s): 
Miles B. Markus
Reference: 
Journal of the History of Biology (2011) 44:781–786
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medsynth@yahoo.co.uk

Hypnozoites are dormant forms in the life cycles of certain parasitic protozoa that belong to the Phylum Apicomplexa (Sporozoa) and are best known for their probable association with latency and relapse in human malarial infections caused by Plasmodium ovale and P. vivax. 

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Review: Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination

Submitted by Kabogo on February 26, 2010 - 10:45
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Author(s): 
Timothy N.C. Wells, Jeremy N. Burrows, J. Kevin Baird
Reference: 
Trends in Parasitology, Volume 26, Issue 3, March 2010, Pages 145-151
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Contact email: 
wellst@mmv.org

The only clinical therapy against relapse of vivax malaria is the 8-aminoquinoline, primaquine. New, safer and more-easily administered drugs are urgently needed, and this is a crucial gap in the broader malaria-elimination agenda.

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