inhibitors

In the present work, QSAR and molecular docking studies have been performed on triazolopyrimidine-based dihydroorotate dehydrogenase (DHODH) inhibitors as antimalarial agents.

In this perspective, we propose that the development of small molecule inhibitors of the Duffy antigen, the portal of infection of P. vivax, would be a novel and potentially effective approach for treating this form of malaria.