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malarial immune evasion

Review: IgM, FcµRs, and Malarial Immune Evasion

Submitted by Kabogo on April 22, 2010 - 12:03
Tags:
Author(s): 
Daniel M. Czajkowsky, Ali Salanti, Sisse B. Ditlev, Zhifeng Shao, Ashfaq Ghumra, J. Alexandra Rowe, and Richard J. Pleass
Reference: 
J. Immunol., May 2010; 184: 4597 – 4603
Access: 
Click here to go to the Journal
Contact email: 
richard.pleass@nottingham.ac.uk

IgM is an ancestral Ab class found in all jawed vertebrates, from sharks to mammals. This ancient ancestry is shared by malaria parasites (genus Plasmodium) that infect all classes of terrestrial vertebrates with whom they coevolved.

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