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Open Access | Plasmodium falciparum FIKK Kinase Members Target Distinct Components of the Erythrocyte Membrane

Submitted by Kabogo on July 29, 2010 - 11:46
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Author(s): 
Marta C. Nunes, Mami Okada, Christine Scheidig-Benatar, Brian M. Cooke, Artur Scherf
Reference: 
PLoS ONE 5(7): e11747
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Click here to go to the full article
Contact email: 
ascherf@pasteur.fr

Our results suggest that FIKK members phosphorylate different membrane skeleton proteins of the infected erythrocyte in a stage-specific manner, inducing alterations in the mechanical properties of the parasite-infected red blood cell.

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The IC50 of anti-Pfs25 antibody in membrane-feeding assay varies among species

Submitted by patrick sampao on June 2, 2010 - 12:03
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Author(s): 
Lediya C., Yimin W., et al.
Reference: 
Vaccine, Volume 28, Issue 27, 17 June 2010, Pages 4423-4429
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Click here to go to the Journal
Contact email: 
kmiura@niaid.nih.gov

In this study, we purified Pfs25-specific IgGs to convert antibody titer to μg/mL and determined the amount of antibody required to inhibit 50% of oocyst development (IC50).

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