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Malaria vaccine efficacy: overcoming the helminth hurdle

Submitted by Kabogo on July 19, 2010 - 13:26
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Author(s): 
JV Cruz-Chan, M Rosado-Vallado, E Dumonteil
Reference: 
Expert Review of Vaccines, July 2010, Vol. 9, No. 7, Pages 707-711
Access: 
Click here to go to the Journal
Contact email: 
oliver@uady.mx

Several studies have documented that helminth infections can interfere with the development of the immune response of vaccines against different diseases, although some results have been contradictory.

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Open Access | Low doses of killed parasite in CpG elicit vigorous CD4+ T cell responses against blood-stage malaria in mice

Submitted by Kabogo on July 19, 2010 - 12:16
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Author(s): 
A Pinzon-Charry, V McPhun, V Kienzle, C Hirunpetcharat, C Engwerda, J McCarthy, MF Good
Reference: 
J Clin Invest, July 12, 2010
Access: 
Click here to go to the full article
Contact email: 
Michael.Good@qimr.edu.au

Development of a vaccine that targets blood-stage malaria parasites is imperative if we are to sustainably reduce the morbidity and mortality caused by this infection.

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