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Association of Microsatellite Variations of Plasmodium falciparum Na+/H+ Exchanger (Pfnhe-1) Gene with Reduced In Vitro Susceptibility to Quinine: Lack of Confirmation in Clinical Isolates from Africa

Submitted by patrick sampao on May 4, 2010 - 13:56
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Author(s): 
Valérie Andriantsoanirina, Didier Ménard, Stéphane Rabearimanana, Véronique Hubert, Christiane Bouchier, Magali Tichit, Jacques Le Bras, and Rémy Durand
Reference: 
Am J Trop Med Hyg, May 2010; 82: 782 - 787.
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Contact email: 
remy.durand@avc.aphp.fr

We concluded that the studied polymorphisms in Pfnhe-1 did not appear as valid molecular markers of in vitro susceptibility to quinine in P. falciparum isolates from Africa.

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