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Pf332-C231

Immunogenicity and antigenic properties of Pf332-C231, a fragment of a non-repeat region of the Plasmodium falciparum antigen Pf332

Submitted by patrick sampao on April 22, 2010 - 12:03
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Author(s): 
H.A. Balogun, N.-M. Vasconcelos, R. Lindberg, M. Haeggström, K. Moll, Q. Chen, M. Wahlgren, K. Berzins
Reference: 
Vaccine, Volume 28, Issue 1, 10 December 2009, Pages 90-97
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Contact email: 
klavs@imun.su.se

Detailed functional studies on the antigen have remained hampered by the cross-reactive nature of antibodies generated to Pf332. Pf332-C231, identified in the C-terminal region of Pf332 was cloned and antibodies against the C231 fragment were shown to react with intact Pf332 antigen by both immunofluorescence and immunoblotting analyses.

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Immunogenicity and antigenic properties of Pf332-C231, a fragment of a non-repeat region of the Plasmodium falciparum antigen Pf332.

Submitted by Kabogo on December 3, 2009 - 12:08
Tags:
Author(s): 
H.A. Balogun, N.-M. Vasconcelos, R. Lindberg, M. Haeggström, K. Moll, Q. Chen, M. Wahlgren, K. Berzins
Reference: 
Vaccine, Volume 28, Issue 1, 10 December 2009, Pages 90-97, doi:10.1016/j.vaccine.2009.09.110
Access: 
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Contact email: 
klavs@imun.su.se

Antigen Pf332, a megadalton protein has been shown to be associated with the membrane of infected erythrocytes. Detailed functional studies on the antigen have remained hampered by the cross-reactive nature of antibodies generated to Pf332.

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