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t-cell

Opinion: Regulatory T cells in malaria – friend or foe?

Author(s): 
Olivia C. Finney, Eleanor M. Riley and Michael Walther
Reference: 
Trends in Immunology, Volume 31, Issue 2, February 2010, Pages 63-70
Contact email: 
mwalther@mrc.gm

Here, we review these studies, focussing in particular on recent studies in humans, propose a model by which different regulatory T cell populations might contribute to the control of inflammation at different stages of infection and discuss the implications for the design of safe and effective malaria vaccines.

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