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Rethinking cerebral malaria pathology

Author(s): 
Milner, Danny A Jr
Reference: 
Current Opinion in Infectious Diseases: October 2010 - Volume 23 - Issue 5 - p 456–463

As we close the gaps in the fight against global malaria, the question of cerebral malaria mortality remains a source of great concern.

Geographic medicine: Effect of different hosts on feeding patterns and mortality of mosquitoes (Diptera: Culicidae) and their implications on parasite transmission

Author(s): 
Eliningaya J Kweka, Beda J Mwang'onde, Lucile Lyaruu, Filemoni Tenu, Aneth M Mahande
Reference: 
Journal of Global Infectious Diseases, Volume 2 : 2 Page : 121-123, 2010
Contact email: 
pat.kweka@gmail.com

We investigated the feeding and mortality rates of three mosquito species, namely Culex quinquefasciatus, Aedes aegypti and Anopheles arabiensis against three different hosts.

Open Access | Cost Savings with Rapid Diagnostic Tests for Malaria in Low-Transmission Areas: Evidence from Dar es Salaam, Tanzania

Author(s): 
Joshua Yukich, Valerie D'Acremont, Judith Kahama, Ndeniria Swai, AND Christian Lengeler
Reference: 
Am J Trop Med Hyg, Jul 2010; 83: 61 - 68.
Contact email: 
jyukich@tulane.edu

Data on costs were collected from 259 patients in 6 health facilities by using exit and in-charge interviews and record reviews during a trial of RDT rollout in Dar es Salaam, Tanzania.

Open Access | Using serological measures to monitor changes in malaria transmission in Vanuatu

Author(s): 
Cook J, Reid H, Iavro J, Kuwahata M, Taleo G, Clements A, McCarthy J, Vallely A, Drakeley C
Reference: 
Malaria Journal 2010, 9:169 (16 June 2010)
Contact email: 
Jackie.Cook@lshtm.ac.uk

Seroepidemiology can provide key information on malaria transmission for control programmes, when parasite rates are low. As Vanuatu moves closer to malaria elimination, monitoring changes in transmission intensity and identification of residual malaria foci is paramount in order to concentrate intervention efforts.

Open Access | The impact of human reservoir of malaria at a community-level on individual malaria occurrence in a low malaria transmission setting along the Thai-Myanmar border

Author(s): 
Lawpoolsri S, Chavez IF, Yimsamran S, Puangsa-art S, Thanyavanich N, Maneeboonyang W, Chaimungkun W, Singhasivanon P, Maguire JH, Hungerford LL
Reference: 
Malaria Journal 2010, 9:143 (26 May 2010)
Contact email: 
tmslw@mahidol.ac.th

In a small area with low malaria transmission intensity, the variation in mosquito abundance is relatively similar across the residential areas; incidence of malaria between hamlets, which reflects the community level of human infectious reservoirs, is an important predictor for the malaria risk among individuals within these hamlets.

Review: Malaria gametocytogenesis

Author(s): 
David A. Baker
Reference: 
Molecular and Biochemical Parasitology, Volume 172, Issue 2, August 2010, Pages 57-65
Contact email: 
david.baker@lshtm.ac.uk

Recent transcriptome, proteome and reverse genetic studies have added valuable information to that obtained from traditional studies. However, we still have no answer to the fundamental question regarding sexual development: ‘what triggers gametocytogenesis’?

Open Access | Bionomics of Anopheline species and malaria transmission dynamics along an altitudinal transect in Western Cameroon

Author(s): 
Timoleon T., Frederic S., et al.
Reference: 
BMC Infectious Diseases 2010, 10:119
Contact email: 
timtchuinkam@yahoo.fr

Sampled Anopheles were tested for the presence of Plasmodium circumsporozoite proteins and their blood meal origin with ELISA. Entomological parameters of malaria epidemiology were assessed using Mac Donald's formula.

Protective hemoglobinopathies and Plasmodium falciparum transmission

Author(s): 
Geoffrey Pasvol
Reference: 
Nature Genetics 42, 284-285 (April 2010)
Contact email: 
g.pasvol@imperial.ac.uk

A new study demonstrates that such genetic variation may also be associated with increased transmission of this pathogen from the human host to the Anopheles vector.

Open Access | Blocking of Plasmodium transmission by cooperative action of Cecropin A and Defensin A in transgenic Aedes aegypti mosquitoes

Author(s): 
V Kokoza, A Ahmed, S Woon Shin, N Okafor, Z Zou, AS Raikhel
Reference: 
PNAS April 13, 2010, 107 (15)
Contact email: 
alexander.raikhel@ucr.edu

To overcome burden of mosquito-borne diseases, multiple control strategies are needed. Population replacement with genetically modified mosquitoes carrying antipathogen effector genes is one of the possible approaches for controlling disease transmission.

Disentangling the Effect of Local and Global Spatial Variation on a Mosquito-Borne Infection in a Neotropical Heterogeneous Environment

Author(s): 
María-Eugenia Grillet, Roberto Barrera, Juan-Eudes Martínez, Jesús Berti, AND Marie-Josée Fortin
Reference: 
Am J Trop Med Hyg 2010;82 194-201
Contact email: 
maria.grillet@ciens.ucv.ve

We used local spatial statistics and geographically weighted regression (GWR) to determine the spatial pattern of malaria incidence and persistence in northeastern Venezuela.

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