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anti-malarial drug

Open Access | Expanding the Antimalarial Drug Arsenal—Now, But How?

Author(s): 
Brian T. Grimberg and Rajeev K. Mehlotra
Reference: 
Pharmaceuticals 2011, 4(5), 681-712
Contact email: 
brian.grimberg@case.edu

The number of available and effective antimalarial drugs is quickly dwindling.

Anti-malarial drug formulations and novel delivery systems: A review

Author(s): 
P. Murambiwa, B. Masola, T. Govender, S. Mukaratirwa, C.T. Musabayane
Reference: 
Acta Tropica, Volume 118, Issue 2, May 2011, Pages 71-79
Contact email: 
musabayanec@ukzn.ac.za

Artemisinin combination therapies have decreased malaria associated morbidity and mortality in several parts of the world.

Open Access | Implementation of a reference standard and proficiency testing programme by the World Wide Antimalarial Resistance Network (WWARN)

Author(s): 
Lourens C, Watkins WM, Barnes KI, Sibley CH, Guerin PJ, White NJ, Lindegardh N
Reference: 
Malaria Journal 2010, 9:375 (25 December 2010)
Contact email: 
chris.lourens@wwarn.org

The proficiency testing programme is designed as a cooperative effort to help participating laboratories assess their ability to carry out drug analysis, resolve any potential problem areas and to improve their results - and, in so doing, to improve the quality of anti-malarial pharmacokinetic data published and shared with WWARN.

Open Access | SMS for Life: a pilot project to improve anti-malarial drug supply management in rural Tanzania using standard technology

Author(s): 
Barrington J, Wereko-Brobby O, Ward P, Mwafongo W, Kungulwe S
Reference: 
Malaria Journal 2010, 9:298 (27 October 2010)
Contact email: 
jim.barrington@novartis.com

The SMS for Life pilot provided visibility of anti-malarial stock levels to support more efficient stock management using simple and widely available SMS technology, via a public-private partnership model that worked highly effectively.

Open Access | Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya

Author(s): 
Watsierah CA, Jura WG, Oyugi H, Abong'o B, Ouma C
Reference: 
Malaria Journal 2010, 9:295 (26 October 2010)
Contact email: 
carrenwat@yahoo.com

This study demonstrates that consumers require access to correct and comprehensible information associated with use of drugs, including self-prescription.

Open Access | Opinion:CPP-ZFN: A potential DNA-targeting anti-malarial drug

Author(s): 
Vikrant Nain, Shakti Sahi, Anju Verma
Reference: 
Malaria Journal 2010, 9:258
Contact email: 
vikrant@gbu.ac.in

Targeting of the Plasmodium genome using ZFN has great potential for the development of anti-malarial drugs. It allows the development of a single drug against all malarial infections, including multidrug-resistant strains.

Open Access | Prospective strategies to delay the evolution of anti-malarial drug resistance: weighing the uncertainty

Author(s): 
Smith DL, Klein EY, McKenzie F, Laxminarayan R
Reference: 
Malaria Journal 2010, 9:217 (23 July 2010)
Contact email: 
davesmith@ufl.edu

At a global scale, because of uncertainty about the time to the emergence of ACT resistance, there was a strong case for MFTs to guard against early failure.

Open Access | CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives

Author(s): 
Boulton IC, Nwaka S, Bathurst I, Lanzer M, Taramelli D, Vial H, Doerig C, Chibale K, Ward SA
Reference: 
Malaria Journal 2010, 9:202 (13 July 2010)

Despite increasing efforts and support for anti-malarial drug R&D, globally anti-malarial drug discovery and development remains largely uncoordinated and fragmented.

Open Access | Anti-malarial drug quality in Lagos and Accra - a comparison of various quality assessments

Author(s): 
Bate R, Hess K
Reference: 
Malaria Journal 2010, 9:157 (11 June 2010)
Contact email: 
rbate@aei.org

The evidence presented shows that drug quality is probably improving in both cities, especially Lagos, since major reductions of failure rates over time occur with all means of assessment. Many more samples failed when examined by Raman spectrometry than by Minilab protocol.

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