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IL4-590C/T polymorphism

Open Access | IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria

Submitted by Inga on December 14, 2009 - 11:49
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Author(s): 
Piyatida Tangteerawatana, Hedvig Perlmann, Masashi Hayano, Thareerat Kalambaheti, Marita Troye-Blomberg, Srisin Khusmith
Reference: 
Malaria Journal 2009, 8:286 (10 December 2009)
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Contact email: 
tmskm@mahidol.ac.th

The results suggest that IL4-590C or T alleles participated differently in the regulation of anti-malarial antibody isotype profiles in primary and secondary malaria infection and, therefore, could play an important role in alteration of malaria severity.

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