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Open Access | Additive In Vitro Antiplasmodial Effect of N-Alkyl and N-Benzyl-1,10-Phenanthroline Derivatives and Cysteine Protease Inhibitor E64

Submitted by patrick sampao on August 25, 2010 - 14:11
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Author(s): 
Mahardika Agus Wijayanti, Eti Nurwening Sholikhah, Ruslin Hadanu, Jumina Jumina, Supargiyono Supargiyono and Mustofa Mustofa
Reference: 
Malaria Research and Treatment, Volume 2010 (2010)
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dikafkugm@yahoo.co.id

As the interaction of chloroquine and E64 was additive, the results indicated that these new compounds had a mechanism of action by inhibiting Plasmodium proteases.

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