quinine

Data from the present study put doubt regarding the pfnhe-1 gene as to whether it could be used as the suitable marker for QN resistance in Thailand.

The evidence on the efficacy of clindamycin plus quinine as an alternative treatment for uncomplicated malaria is inconclusive.

Plasmodium falciparum isolates with decreased susceptibility to quinine are increasingly being found in malaria patients.

Rapid and fast acting anti-malarials are essential to treat severe malaria.

The haplotype 7 which is the typical Asian profile is likely well-adapted to high drug pressure in this area and may constitute a good genetic marker to evaluate the dissemination of QNR in this part of the world.

In this report, we have reviewed work on the in vivo efficacy and in vitro activity of quinine, and discussed recent data on genetic markers of resistance to this drug.

Two authors independently assessed the eligibility and risk of bias of trials, and extracted and analysed data.

A simple modification of a flow cytometer allows for rapid and reliable detection and quantification of Hz-containing leukocytes and the analysis of differential surface marker expression in the same sample of Hz-containing versus non-Hz-containing leukocytes.

The roots of cryptolepis, also known as nibima, kadze, gangamau, Ghanaian quinine and yellow-dye root (Cryptolepis sanguinolenta) have been used in Ghana-ian traditional medicine for treatment of malaria for many generations.

The polymorphism in the microsatellite ms4760 in Pfnhe-1 that cannot be used to monitor quinine response in the regions of the Republic of Congo, where the isolates came from.