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Diagnosis and Therapy for Hospitalized Imported Malaria in Adults in Italy

Author(s): 
Spinello Antinori, Barbara Cigardi, Laura Galimberti, Giovanna Orlando, Luca Schifanella, Laura Milazzo, Anita Viola, Giuseppe Giuliani, Annalisa Ridolfo and Mario Corbellino
Reference: 
Journal of Travel Medicine, Volume 18, Issue 6, pages 379–385, November/December 2011
Contact email: 
spinello.antinori@unimi.it

MalariaWorldIn our study more than two thirds of imported malaria cases were due to P falciparum with an excess of cases diagnosed in immigrants starting from the year 2000.

Open Access | Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

Author(s): 
Panda AK, Panda SK, Sahu AN, Tripathy R, Ravindran B, Das BK
Reference: 
Malaria Journal 2011, 10:309 (19 October 2011)
Contact email: 
adityarmrc@gmail.com

MalariaWorldResults of the current study indicate that blood group 'O' is associated with reduced and 'B' blood group with increased risk of development of severe malaria in Odisha, India.

Open Access | A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720

Author(s): 
James S. McCarthy, Joanne Marjason, Robin F. Anders, et al.
Reference: 
PLoS ONE 6(9): e24413
Contact email: 
J.McCarthy@uq.edu.au

MalariaWorldAs the majority of subjects vaccinated with MSP2-C1 developed an antibody responses to both forms of MSP2, and that these antibodies mediated ADCI provide further support for MSP2 as a malaria vaccine candidate.

Open Access | A Small Amount of Fat Does Not Affect Piperaquine Exposure in Patients with Malaria

Author(s): 
Anna Annerberg, Khin Maung Lwin, Niklas Lindegardh, Sakchai Khrutsawadchai, Elizabeth Ashley, Nicholas P. J. Day, Pratap Singhasivanon, Joel Tarning, Nicholas J. White, and François Nosten
Reference: 
Antimicrobial Agents and Chemotherapy, September 2011,p. 3971-3976, Vol. 55, No. 9
Contact email: 
niklas@tropmedres.ac

Dihydroartemisinin-piperaquine is a new, highly effective, and well-tolerated combination treatment for uncomplicated falciparum malaria.

Open Access | Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults

Author(s): 
Dodoo D, Hollingdale MR, Anum D, Koram KA, Gyan B, Akanmori BD, Ocran J, Adu-Amankwah S, Ganeshan H, Abot E, Legano J, Banania G, Sayo R, Brambilla D, Kumar S, Doolan DL, Rogers WO, Epstein J, Richie TL, Sedegah M
Reference: 
Malaria Journal 2011, 10:168 (20 June 2011)
Contact email: 
DDodoo@noguchi.mimcom.org

All participants were positive for at least one malaria protein by ELISA, with results dependent on the criteria for positivity.

Open Access | Low prevalence of Plasmodium falciparum antigenaemia among asymptomatic HAART-treated adults in an urban cohort in Uganda

Author(s): 
Nakanjako D, Kiragga AN, Castelnuovo B, Kyabayinze DJ, Kamya MR
Reference: 
Malaria Journal 2011, 10:66 (22 March 2011)
Contact email: 
drdamalie@yahoo.com

In an urban area of low to moderate stable malaria transmission, there was low HRP2 P. falciparum antigenaemia among PLHIV after long-term HAART and cotrimoxazole prophylaxis.

Effect of artesunate and mefloquine in combination on the Fridericia corrected QT intervals in Plasmodium falciparum infected adults from Thailand

Author(s): 
S. Krudsood, S. Looareesuwan, P. Wilairatama, W. Leowattana, N. Tangpukdee, K. Chalermrut, S. Ramanathan, V. Navaratnam, P. Olliaro, M. Vaillant, J. R. Kiechel and W. R. J. Taylor
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 4, pages 458–465, April 2011
Contact email: 
bob@tropmedres.ac

In this small group of patients, slowing heart rates due to malaria resolution best explained the observed increases in the QTcF intervals.

Open Access | Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations

Author(s): 
Nkoghe D, Akue J, Gonzalez J, Leroy EM
Reference: 
Malaria Journal 2011, 10:33 (9 February 2011)
Contact email: 
dnkoghe@hotmail.com

Plasmodium falciparum carriage remains high among adults in rural Gabon. Control measures must be adapted to the region and ecosystem. Routine treatment of asymptomatic individuals should be considered.

Schistosoma mansoni: Schistosomicidal effect of mefloquine and primaquine in vitro

Author(s): 
M.C. Holtfreter, M. Loebermann, S. Klammt, M. Sombetzki, P. Bodammer, D. Riebold, R. Kinzelbach, E.C. Reisinger
Reference: 
Experimental Parasitology, Volume 127, Issue 1, January 2011, Pages 270-276

We investigated the effects of the anti-malarials mefloquine and primaquine against the juvenile and adult life stages of Schistosoma mansoni in vitro.

Open Access | Is staying overnight in a farming hut a risk factor for malaria infection in a setting with insecticide-treated bed nets in rural Laos?

Author(s): 
Open Access | Is staying overnight in a farming hut a risk factor for malaria infection in a setting with insecticide-treated bed nets in rural Laos?
Reference: 
Malaria Journal 2010, 9:372 (23 December 2010)
Contact email: 
laodaisuke@hotmail.co.jp

This study showed that staying overnight in farming huts was not associated with an increased risk of malaria infection in the setting where ITNs were widely used in farming huts.

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