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Placental Malaria and Mother-to-Child Transmission of Human Immunodeficiency Virus-1 in Rural Rwanda

Author(s): 
Philip L. Bulterys, Ann Chao, Sudeb C. Dalai, M. Christine Zink, Abel Dushimimana, David Katzenstein, Alfred J. Saah and Marc Bulterys
Reference: 
Am J Trop Med Hyg 2011 vol. 85 no. 2 202-206
Contact email: 
bulterys@ucla.edu

We conducted a nested case-control study of placental malaria (PM) and mother-to-child transmission (MTCT) of human immunodeficiency virus-1 (HIV-1) within a prospective cohort of 627 mother-infant pairs followed from October 1989 until April 1994 in rural Rwanda.

On the validity of self-reports and indirect reports to ascertain malaria prevalence in settings of hypoendemicity

Author(s): 
Mathieu Maheu-Giroux, Martín Casapía, Theresa W. Gyorkos
Reference: 
Social Science & Medicine, Volume 72, Issue 5, March 2011, Pages 635-640
Contact email: 
theresa.gyorkos@mcgill.ca

The aim of our research was to determine the validity of self-report and indirect report in ascertaining malaria prevalence over six, eighteen and thirty-month time periods. Reports of malaria episodes collected through interviewer-administered questionnaires (193 self-reports, 614 indirect reports) were compared to microscopy-confirmed cases (principally Plasmodium vivax) registered at a government-run health post in the Peruvian Amazon.

Iron Homeostasis in Mother and Child during Placental Malaria Infection

Author(s): 
Susanne Van Santen, Quirijn de Mast, Adrian J. F. Luty, Erwin T. Wiegerinck, Andre J. A. M. Van der Ven, AND Dorine W. Swinkels
Reference: 
Am J Trop Med Hyg, Jan 2011; 84: 148 - 151.
Contact email: 
d.swinkels@labgk.umcn.nl

We conclude that maternal hepcidin is not significantly altered as a function of placental infection and/or anemia. Importantly, fetal hemoglobin and iron status were also unaffected, regardless of the presence of placental infection or maternal anemia.

Adult and child malaria mortality in India: a nationally representative mortality survey

Author(s): 
The Lancet, Volume 376, Issue 9754, 20 November 2010-26 November 2010, Pages 1768-1774
Reference: 
Neeraj Dhingra., Prabhat Jha., Richard Peto., et al.
Contact email: 
prabhat.jha@utoronto.ca

We aimed to estimate plausible ranges of malaria mortality in India, the most populous country where the disease remains common.

Open Access | Scaling Up Malaria Control in Zambia: Progress and Impact 2005–2008

Author(s): 
Elizabeth C., John M., et al.
Reference: 
Am. J. Trop. Med. Hyg., 83(3), 2010, pp. 480-488
Contact email: 
elizabethchizema@yahoo.co.uk

Zambia national survey, administrative, health facility, and special study data were used to assess progress and impact in national malaria control between 2000 and 2008.

Open Access | Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine

Author(s): 
Ouattara A, Mu J, Takala-Harrison S, Saye R, Sagara I, Dicko A, Niangaly A, Duan J, Ellis RD, Miller LH, Su X, Plowe CV, Doumbo OK
Reference: 
Malaria Journal 2010, 9:175 (21 June 2010)

This Phase 2 trial of a bivalent AMA1 malaria vaccine found no evidence of vaccine selection or strain-specific efficacy, suggesting that the extreme genetic diversity of AMA1 did not account for failure of the vaccine to provide protection.

Red Cells, Iron, and Erythropoiesis: Differing effects of HbS and HbC traits on uncomplicated falciparum malaria, anemia, and child growth

Author(s): 
Benno K., Christina K., et al.
Reference: 
Blood, Jun 2010; 115: 4551 - 4558.

Infants with HbAS were protected from uncomplicated malaria (P < .005) and anemia (P < .001), had lower age-adjusted parasite densities (P < .001), and higher age-adjusted hemoglobin levels compared with children with the HbAA genotype (P = .004).

Clinical Picture: Malarial retinopathy and fluorescein angiography findings in a Malawian child with cerebral malaria

Author(s): 
Simon J Glover, Richard J Maude, Terrie E Taylor, Malcolm E Molyneux, Nicholas AV Beare
Reference: 
The Lancet Infectious Diseases, Volume 10, Issue 6, June 2010, Page 440
Contact email: 
richardmaude@gmail.com

No abstract available

Open Access | School-based participatory health education for malaria control in Ghana: engaging children as health messengers

Author(s): 
Ayi I, Nonaka D, Adjovu JK, Hanafusa S, Jimba M, Bosompem KM, Mizoue T, Takeuchi T, Boakye DA, Kobayashi J
Reference: 
Malaria Journal 2010, 9:98 (18 April 2010)
Contact email: 
IAyi@noguchi.mimcom.org

School children have been increasingly recognized as health messengers for malaria control. However, little evidence is available. The objective of this study was to determine the impact of school-based malaria education intervention on school children and community adults

Editorial: Antimicrobials in children admitted to hospital in malaria endemic areas

Author(s): 
Kathryn Maitland
Reference: 
BMJ 2010;340:c1818
Contact email: 
kathryn.maitland@gmail.com

This study highlights the inadequacy of the time honoured antibiotics that are in routine use across Africa, and that are likely to remain unchanged even after immunisation for H influenzae and S pneumoniae is introduced into malaria endemic Africa.

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