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We conducted a nested case-control study of placental malaria (PM) and mother-to-child transmission (MTCT) of human immunodeficiency virus-1 (HIV-1) within a prospective cohort of 627 mother-infant pairs followed from October 1989 until April 1994 in rural Rwanda.
The aim of our research was to determine the validity of self-report and indirect report in ascertaining malaria prevalence over six, eighteen and thirty-month time periods. Reports of malaria episodes collected through interviewer-administered questionnaires (193 self-reports, 614 indirect reports) were compared to microscopy-confirmed cases (principally Plasmodium vivax) registered at a government-run health post in the Peruvian Amazon.
We conclude that maternal hepcidin is not significantly altered as a function of placental infection and/or anemia. Importantly, fetal hemoglobin and iron status were also unaffected, regardless of the presence of placental infection or maternal anemia.
We aimed to estimate plausible ranges of malaria mortality in India, the most populous country where the disease remains common.
Zambia national survey, administrative, health facility, and special study data were used to assess progress and impact in national malaria control between 2000 and 2008.
This Phase 2 trial of a bivalent AMA1 malaria vaccine found no evidence of vaccine selection or strain-specific efficacy, suggesting that the extreme genetic diversity of AMA1 did not account for failure of the vaccine to provide protection.
Infants with HbAS were protected from uncomplicated malaria (P < .005) and anemia (P < .001), had lower age-adjusted parasite densities (P < .001), and higher age-adjusted hemoglobin levels compared with children with the HbAA genotype (P = .004).
No abstract available
School children have been increasingly recognized as health messengers for malaria control. However, little evidence is available. The objective of this study was to determine the impact of school-based malaria education intervention on school children and community adults
This study highlights the inadequacy of the time honoured antibiotics that are in routine use across Africa, and that are likely to remain unchanged even after immunisation for H influenzae and S pneumoniae is introduced into malaria endemic Africa.