traveller

The authors report a case of a healthy young man diagnosed with PCR negative cerebral malaria, a week after returning from Mumbai.

Although the diagnostic value of neopterin and procalcitonin is limited, the high negative predictive value of both neopterin and procalcitonin may be helpful for a rapid exclusion of severe malaria disease on admission.

The general public (potential travellers), were more tolerant of taking prophylaxis if associated with no or mild AEs and least tolerant of mild sequelae from malaria and severe drug related events. The rating value reported for taking no prophylaxis was quite variable.

he scope of this review is the prevention of Plasmodium falciparum, which is the malaria species that causes the overwhelming majority of severe disease and death, and which in many areas of the world is frequently resistant to the classical antimalarial agent chloroquine.

The objective of this study was to assess malaria protection measures in European travellers as a function of the risk of infection with malaria. 

Commentary on:
Jacquerioz FA, Croft AM . Drugs for preventing malaria in travellers. Cochrane Database Syst Rev 2009:CD006491.

Risk estimates based on mathematical modeling based on accurate data can be a valuable tool in assessing risk/benefits and cost/benefits when deciding on the value of interventions for travellers to malaria endemic regions.

Further work is required to ascertain whether ease of use and compliance may be important factors in the outcomes associated with malariachemoprophylaxis.