Reply to: Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum
What is the aconite orocrycum
Reply to: Should Artemisia annua (wormwood) tea be used as a prophylactic in endemic countries?
Poppycock to the Guest who claims use of the tea will create resistance and will lead to short supplies. Parsley grows in anyone's back garden. Artemisia annua can do the same. A resistance to synthetic artemisia analogues has already happened and the increased dosage of these synthetic drugs, resorted to in response, is causing other life threatening complications in patients. For what purpose? To make more money for the patent holder? Your argument does not stack up with any sensible reader. Grow the tea, it's a more humane solution.
Reply to: NOT Open Access | Plasmodium vivax malaria in the UK
I am very interested to know about the reason why is P.vivax is increasing nowadays than previous time. I think as it is in the journal it could be the global warming. In addition it could be the drug resistance issue and the relapsing behavior of P.vivax.
Reply to: World Malaria day: Vestergaard infographic about insecticide resistance
We have ample evidence on the efficacy of PN3.0 in areas with metabolic-based resistance mechanism. We know it works. We must strategise its usage for maximal impact.
Reply to: Geophagia, Artemisia afra and Tuberculosis
The document posted by Pierre Lutgen opens an interesting door. Because the use of plants against tuberculosis and leprosy is documented in the literature.
Already in 1923 the Transactions of the Royal Society of Tropical Medicine and Hygiene (M Hamzah, vol 17, 6-7, 386-391) described the results of treating leprosy with thymol: Disappearance of the irritating feeling on the face as well as the shooting pains in the muscles after a few injections. Drying up of the secretions of the ulcers after a few injections followed by complete healing of the ulcers. Flattening and general disappearance of the leprotic nodules which in the beginning were erythematous. In a few patients marked pigment spots took the places of the scars, but these were slowly resorbed and the skin regained its normal colour.
But phytomedicine confronted by pharmaceutical monotherapies declined for 100 year.
It is reviving, mostly under the pressure of research done in Southern countries. In 1992 Khadija Rhayour dedicated her Thesis at the University of Fès to the bactericidal action of essential oils of Thyme, Rosemary and Artemisia and found that all three were active against Mycobacteria. The monoterpenes thymol, carvacrol and eugenol were the strongest. Eugenol is well present in Syzygium aromaticum (clove).
A Pakistanese team studied two Origanum species and found that Origanum vulgaris had the best antibacterial properties. It contained thymol and carvacrol absent in Origanum majorana (A Hussain et al., Revista Brasileira de Pharmacognosis, 2011, 21, 943-952).
The Gauhaty University of India also made a survey of medicinal plants used against leprosy (SJ Deka et al., Plant Archives 2007, 7, 653-655).
A research team in Nigeria (O.I Faleyimu et al., AJOL, 8, 2009) examined the use of medicinal plants in the treatment of tuberculosis,. Eighty randomly selected questionnaires were administered to traditional healers, herbs traders, farmers and civil servants in the Local Government and were interviewed on the use of forest plants in the treatment of tuberculosis.
This study has proved that local people have a wealth of knowledge that needs to be the focal point in pharmaceutical research.