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Scientific Articles

NOT Open Access | Hemocyte differentiation mediates the mosquito late-phase immune response against Plasmodium in Anopheles gambiae

July 1, 2015 - 15:44 -- NOT Open Access
Author(s): 
Ryan C. Smith, Carolina Barillas-Mury, and Marcelo Jacobs-Lorena
Reference: 
PNAS June 30, 2015 vol. 112 no. 26 E3412-E3420

Plasmodium parasites must complete development in the mosquito vector for transmission to occur.

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NOT Open Access | Sex hormones modulate the immune response to Plasmodium berghei ANKA in CBA/Ca mice

July 1, 2015 - 15:41 -- NOT Open Access
Author(s): 
Martha Legorreta-Herrera, Néstor Aarón Mosqueda-Romo, Karen Elizabeth Nava-Castro, Ana Laura Morales-Rodríguez, Fidel Orlando Buendía-González & Jorge Morales-Montor
Reference: 
Parasitology Research, July 2015, Volume 114, Issue 7, pp 2659-2669

Susceptibility to malaria differs between females and males, and this sexual dimorphism may have important implications for the effects of vaccines and drugs.

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Malaria in Pregnancy Interacts with and Alters the Angiogenic Profiles of the Placenta

July 1, 2015 - 15:40 -- Open Access
Author(s): 
Ricardo Ataíde, Oscar Murillo, Claudio R. F. Marinho, et al.
Reference: 
PLoS Negl Trop Dis 9(6): e0003824

Malaria in pregnancy remains a substantial public health problem in malaria-endemic areas with detrimental outcomes for both the mother and the foetus.

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Resistance of infection by Plasmodium vivax to chloroquine in Bolivia

July 1, 2015 - 15:37 -- Open Access
Author(s): 
Arletta Añez, Manuel Moscoso, Ángel Laguna, Cecilia Garnica, Viviana Melgar, Mauren Cuba, Sonia Gutierrez, Carlos Ascaso
Reference: 
Malaria Journal 2015, 14:261 (1 July 2015)

The present study demonstrates the presence of resistance to CQ in the treatment of malaria by P. vivax in the Amazon region of Bolivia.

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Seasonal associations of climatic drivers and malaria in the highlands of Ethiopia

June 26, 2015 - 16:00 -- Open Access
Author(s): 
Midekisa A, Beyene B, Mihretie A, Bayabil E, Wimberly MC
Reference: 
Parasites & Vectors 2015, 8 :339 (24 June 2015)

We found that both early and late peak malaria incidence had the strongest associations with meteorological conditions in the preceding dry and early transition seasons.

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Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA

June 25, 2015 - 15:21 -- Open Access
Author(s): 
Kate M Broadbent, Jill C Broadbent, Ulf Ribacke, Dyann Wirth, John L Rinn and Pardis C Sabeti
Reference: 
BMC Genomics 2015, 16:454

We validated the complete splicing structure of three lncRNAs with compelling properties. Non-polyA-selected deep sequencing also enabled the prediction of hundreds of intriguing P. falciparum circular RNAs, six of which we validated experimentally.

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Malaria mapping: understanding the global endemicity of falciparum and vivax malaria

June 25, 2015 - 15:15 -- Open Access
Author(s): 
Ursula Dalrymple, Bonnie Mappin and Peter W. Gething
Reference: 
BMC Medicine 2015, 13:140

In this minireview we consider the main factors that have facilitated the recent proliferation of malaria risk mapping efforts and describe the most prominent global-scale endemicity mapping endeavours of recent years.

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Effect of crude leaf extract of Osyris quadripartita on Plasmodium berghei in Swiss albino mice

June 25, 2015 - 15:12 -- Open Access
Author(s): 
Senait Girma, Mirutse Giday, Berhanu Erko and Hassen Mamo
Reference: 
BMC Complementary and Alternative Medicine 2015, 15:184

Accordingly, this study was aimed at evaluating the anti-malarial activity of Osyris quadripartita Salzm. Ex Decne., a plant which is used for traditional malaria treatment by local people in different parts of Ethiopia.

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Knockdown resistance (kdr) mutations in Indian Anopheles culicifacies populations

June 24, 2015 - 15:40 -- Open Access
Author(s): 
Dykes C, Kushwah R, Das M, Sharma S, Bhatt R, Veer V, Agrawal O, Adak T, Singh O
Reference: 
Parasites & Vectors 2015, 8 :333 (18 June 2015)

This vector is resistant to DDT in most parts of the country with indication of emerging resistance to pyrethroids. Since knockdown resistance (kdr) is known to confer cross-resistance between DDT and pyrethroids owing to a common target site of action, knowledge of prevalence of knockdown resistance (kdr) alleles is important from insecticide resistance management point of view.

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Prevalence of malaria parasitaemia in school children from two districts of Ghana earmarked for indoor residual spraying: a cross-sectional study

June 24, 2015 - 13:58 -- Open Access
Tags: 
Author(s): 
Nimako Sarpong, Ellis Owusu-Dabo, Benno Kreuels, Julius N Fobil, Sylvester Segbaya, Frank Amoyaw, Andreas Hahn, Thomas Kruppa, Jürgen May
Reference: 
Malaria Journal 2015, 14:260 (25 June 2015)

The burden of parasitaemia, malaria and anaemia is a major public health problem among school children in rural Ghana with extensive heterogeneity between schools and warrants further investment in intervention measures.

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