The world's scientific and social network for malaria professionals
8343 malaria professionals are enjoying the free benefits of MalariaWorld today

Scientific Articles

Liver changes in severe Plasmodium falciparum malaria: histopathology, apoptosis and nuclear factor kappa B expression

April 18, 2014 - 15:06 -- Open Access
Author(s): 
Viriyavejakul P, Khachonsaksumet V, Punsawad C
Reference: 
Malaria Journal 2014, 13 :106 (17 March 2014)

This study investigated the liver pathology of severe P. falciparum malaria as well as the regulation and occurrence of apoptosis in cellular components of formalin-fixed, paraffin-embedded liver tissues.

Average: 
0
No votes yet

Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling

April 16, 2014 - 19:05 -- Open Access
Author(s): 
Hodel EM, Kay K, Hayes DJ, Terlouw DJ, Hastings IM
Reference: 
Malaria Journal 2014, 13 :138 (7 April 2014)

The model highlights the sub-optimally low ratio of DHA:PPQ which, in combination with the narrow therapeutic dose range of PPQ compared to DHA that drives the weight or age cut-offs, leaves DHA at a high risk of under-dosing.

Average: 
0
No votes yet

Mind the gaps - the epidemiology of poor-quality anti-malarials in the malarious world - analysis of the WorldWide Antimalarial Resistance Network database

April 16, 2014 - 19:03 -- Open Access
Author(s): 
Tabernero P, Fernández FM, Green M, Guerin PJ, Newton PN
Reference: 
Malaria Journal 2014, 13 :139 (8 April 2014)

The available evidence demonstrates the need for more investment to improve both sampling and analytical methodology and to achieve consensus in defining different types of poor quality medicines.

Average: 
0
No votes yet

PCR targeting Plasmodium mitochondrial genome of DNA extracted from dried blood on filter paper compared to whole blood

April 16, 2014 - 18:59 -- Open Access
Author(s): 
Strøm GE, Moyo S, Fataki M, Langeland N, Blomberg B
Reference: 
Malaria Journal 2014, 13 :137 (7 April 2014)

In this study, PCR for malaria mitochondrial DNA extracted from whole blood was more sensitive than from DBS. However, DBS are a practical alternative to whole blood and detected approximately the same number of cases as RDTs and, therefore, remain relevant for research purposes.

Average: 
0
No votes yet

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

April 16, 2014 - 18:57 -- Open Access
Author(s): 
Behet MC, Foquet L, van Gemert G, Bijker EM, Meuleman P, Leroux-Roels G, Hermsen CC, Scholzen A, Sauerwein RW
Reference: 
Malaria Journal 2014, 13 :136 (5 April 2014)

These data highlight the functional contribution of antibody responses to pre-erythrocytic immunity after whole-parasite immunization against P. falciparum malaria.

Average: 
5
Average: 5 (1 vote)

Two novel mutations of pfdhps K540T and I588F, affecting sulphadoxine-pyrimethamine-resistant response in uncomplicated falciparum malaria at Banjar district, South Kalimantan Province, Indonesia

April 16, 2014 - 18:52 -- Open Access
Author(s): 
Basuki S, Fitriah, Riyanto S, Budiono, Dachlan YP, Uemura H
Reference: 
Malaria Journal 2014, 13 :135 (4 April 2014)

Pfdhfr and pfdhps genotypes from 24 P. falciparum-infected patients consisting of adequate clinical parasitological response (ACPR) (n = 6; 25.0%) and early treatment failure (ETF) (n = 10; 41.7%) or late parasitological failure (LPF) (n = 8; 33.3%) were obtained by sequencing.

Country: 
Average: 
0
No votes yet

Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a longitudinal cohort

April 16, 2014 - 18:48 -- Open Access
Author(s): 
Zhang G, Skorokhod OA, LeSouëf PN, et al.
Reference: 
Malaria Journal 2014, 13 :134 (3 April 2014)

This study is part of a three-arm randomized, double-blind, placebo-controlled trial. Three hundred and twelve children were included in the present study with AOPP levels measured at 2.5, 5.5, 10.5, 15 and 24 months of age.

Average: 
0
No votes yet

Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system

April 16, 2014 - 18:44 -- Open Access
Author(s): 
Herrera-Varela M, Lindh J, Lindsay SW, Fillinger U
Reference: 
Malaria Journal 2014, 13 :133 (2 April 2014)

Here the habitat selection by Anopheles gambiae sensu lato (s.l.), the principal African malaria vector, was investigated when presented with a choice of two infusions made from rabbit food pellets, or soil.

Average: 
5
Average: 5 (1 vote)

Asymptomatic Plasmodium falciparum infection is associated with anaemia in pregnancy and can be more cost-effectively detected by rapid diagnostic test than by microscopy in Kinshasa, Democratic Republic of the Congo

April 16, 2014 - 18:39 -- Open Access
Author(s): 
Matangila JR, Lufuluabo J, Ibalanky AL, Inocêncio da Luz RA, Lutumba P, Van Geertruyden J
Reference: 
Malaria Journal 2014, 13 :132 (2 April 2014)

The aim of this study was to determine the extent of asymptomatic P. falciparum infection, its relation with anaemia as well as the most cost-effective technique for its diagnosis in healthy pregnant women living in Kinshasa, Democratic Republic of the Congo.

Country: 
City: 
Average: 
0
No votes yet

An experimental hut study to quantify the effect of DDT and airborne pyrethroids on entomological parameters of malaria transmission

April 16, 2014 - 18:34 -- Open Access
Author(s): 
Ogoma SB, Lorenz LM, Moore SJ, et al.
Reference: 
Malaria Journal 2014, 13 :131 (1 April 2014)

This study highlights that airborne pyrethroids and DDT affect a range of anopheline mosquito behaviours that are important parameters in malaria transmission, namely deterrence, irritancy/excito-repellency and blood-feeding inhibition.

Average: 
0
No votes yet

Pages

Subscribe to Scientific Articles