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Scientific Articles

Plasmodium knowlesi malaria an emerging public health problem in Hulu Selangor, Selangor Malaysia (2009-2013): epidemiologic and entomologic analysis

September 16, 2014 - 17:04 -- Open Access
Author(s): 
Vythilingam I, Lim YA, Mahmud R, et al.
Reference: 
Parasites & Vectors 2014, 7 :436 (15 September 2014)

In the present study, only An. introlatus was positive for oocysts. Kernel Density analysis showed that P. knowlesi hotspot areas overlapped with areas where the infected An. introlatus was discovered. This further strengthens the hypothesis that An. introlatusis is the vector for P. knowlesi in the Hulu Selangor district.

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Plasmodium falciparum Infection Induces Expression of a Mosquito Salivary Protein (Agaphelin) That Targets Neutrophil Function and Inhibits Thrombosis without Impairing Hemostasis

September 16, 2014 - 15:25 -- Open Access
Author(s): 
Michael Waisberg, Alvaro Molina-Cruz, Ivo M. B. Francischetti, et al.
Reference: 
PLoS Pathog 10(9): e1004338

Blockade of neutrophil elastase emerges as a novel antihemostatic mechanism in hematophagy; it also supports the notion that neutrophils and the innate immune response are targets for antithrombotic therapy.

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Co-infection of Long-Term Carriers of Plasmodium falciparum with Schistosoma haematobium Enhances Protection from Febrile Malaria: A Prospective Cohort Study in Mali

September 16, 2014 - 15:22 -- Open Access
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Author(s): 
Safiatou Doumbo, Tuan M. Tran, Boubacar Traore, et al.
Reference: 
PLoS Negl Trop Dis 8(9): e3154

Co-infection with S. haematobium and P. falciparum is significantly associated with reduced risk of febrile malaria in long-term asymptomatic carriers of P. falciparum.

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Prevalence of asymptomatic malaria and bed net ownership and use in Bhutan, 2013: a country earmarked for malaria elimination

September 16, 2014 - 14:29 -- Open Access
Author(s): 
Wangdi K, Gatton ML, Kelly GC, Clements AC
Reference: 
Malaria Journal 2014, 13 :352 (4 September 2014)

There was high coverage of LLINs in the study area with regular use of LLINs throughout the year.

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NOT Open Access | Pregnancy and Malaria Exposure Are Associated with Changes in the B Cell Pool and in Plasma Eotaxin Levels

September 16, 2014 - 14:23 -- NOT Open Access
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Author(s): 
Pilar Requena, Joseph J. Campo, Carlota Dobaño, et al.
Reference: 
The Journal of Immunology September 15, 2014 vol. 193 no. 6 2971-2983

Pregnancy triggers immunological changes aimed to tolerate the fetus, but its impact on B lymphocytes is poorly understood.

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Evaluation of universal coverage of insecticide-treated nets in western Kenya: field surveys

September 16, 2014 - 14:15 -- Open Access
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Author(s): 
Zhou G, Li JS, Ototo EN, Atieli HE, Githeko AK, Yan G
Reference: 
Malaria Journal 2014, 13 :351 (3 September 2014)

Current methods of delivering ITNs, i.e., one mass campaign every five years and regular distribution of ITNs from health center can barely maintain the current effective coverage.

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Environmental temperatures significantly change the impact of insecticides measured using WHOPES protocols

September 16, 2014 - 14:14 -- Open Access
Author(s): 
Glunt KD, Paaijmans KP, Read AF, Thomas MB
Reference: 
Malaria Journal 2014, 13 :350 (3 September 2014)

A single population of An. stephensi could be classified by WHO criteria as susceptible or resistant to a given chemical, depending on the temperature at which the mosquitoes were exposed.

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Global distribution of malaria-resistant MHC-HLA alleles: the number and frequencies of alleles and malaria risk

September 16, 2014 - 14:12 -- Open Access
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Author(s): 
Garamszegi LZ
Reference: 
Malaria Journal 2014, 13 :349 (3 September 2014)

Therefore, malaria represents a key selection pressure for the human MHC and has left clear evolutionary footprints on both the frequencies and the number of alleles observed in different countries.

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Determinants of delay in care seeking among children under five with fever in Dodoma region, central Tanzania: a cross-sectional study

September 16, 2014 - 14:10 -- Open Access
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Author(s): 
Kassile T, Lokina R, Mujinja P, Mmbando BP
Reference: 
Malaria Journal 2014, 13 :348 (3 September 2014)

Living with non-biological parents, high number of under-fives in household, and long distance to the nearest health facility were important factors for delay in seeking healthcare.

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