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Open Access | Tracing the origins and signatures of selection of antifolate resistance in island populations of Plasmodium falciparum

Submitted by patrick sampao on June 11, 2010 - 08:35
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Author(s): 
Salgueiro P, Vicente JL, Ferreira C, Teofilo V, Galvao A, do Rosario VE, Cravo P, Pinto J
Reference: 
BMC Infectious Diseases 2010, 10:163 (9 June 2010)
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Click here to go to the full article
Contact email: 
psalgueiro@ihmt.unl.pt

This study provides additional evidence for the crucial role of gene flow and drug selective pressures in the rapid spread of SP resistance in P. falciparum populations, from only a few mutation events giving rise to resistance-associated mutants.

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