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Last week at MalariaWorld...how to get your tool to become mainstream

Last week I pondered over what it is that makes new tools or technologies become mainstream in malaria control and elimination. Read the editorial here. Regretfully, I could not come up with a clear answer, but maybe you can - we welcome your comments.

As scientists we deliver new knowledge on malaria, but what is it that makes new inventions become mainstream? That's the question I am struggling with. And, do you consider it (also) our task to make sure that our new inventions are taken up by those practicing malaria control? Are we responsible for the valorisation of our own work?

I am curious how you think about this...
Bart

Enjoy this week's MalariaWorld - the MW team. 

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Last week in MalariaWorld: GM mosquito blog, MR4, SjCOOP, and post-doc position

Busy week again, and much is going on in the field of malaria. The news that a gene drive system is available surfaced in headlines across the world, and Mark Benedict reviewed for us if this is really an important step forward towards the possible use of GM mosquitoes for malaria control. Read what he thinks here. Do you think GM mosquitoes will one day fly to control malaria? Happy to hear your views under Mark's blog.

MR4 has updated and revised its training manual 'Methods in Anopheles research'. Read here what has been added and changed. You can download the manual for free at their website (www.mr4.org).

Another interesting news story within the SjCOOP project, written by journalist Ntaryike Divine Jr. from Douala, Cameroon. This time about the ARCHIVE institute, ready to start improving house designs in Cameroon as a means to control transmission of malaria. Read the story here.

Enjoy this week's MalariaWorld - the MW team.

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Regulation of Anti-Plasmodium Immunity by a LITAF-like Transcription Factor in the Malaria Vector Anopheles gambiae

October 30, 2012 - 08:26 -- Kabogo Ndegwa
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Author(s): 
Ryan C. Smith, Abraham G. Eappen, Andrea J. Radtke, Marcelo Jacobs-Lorena
Reference: 
PLoS Pathog 8(10): e1002965

The mosquito is the obligate vector for malaria transmission

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Molecular analysis of reticulocyte binding protein-2 gene in Plasmodium vivax isolates from India

October 29, 2012 - 06:06 -- Open Access
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Author(s): 
Prajapati SK, Kumari P, Singh OP
Reference: 
BMC Microbiology 2012, 12:243 (24 October 2012)

MalariaWorldThe study suggests that pvrbp-2 is highly polymorphic genetic marker which can be used for population genetic analyses. RFLP analysis suggests presence of nearly similar proportion of Sal-1 and Belem alleles in Indian P. vivax populations. 

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The susceptibility of five African Anopheles species to Anabaena PCC 7120 expressing Bacillus thuringiensis subsp. israelensis mosquitocidal cry genes

October 8, 2012 - 16:34 -- Patrick Sampao
Author(s): 
Ketseoglou I, Bouwer G
Reference: 
Parasites & Vectors 2012, 5:220 (4 October 2012)

MalariaWorldThe aim of this study was to evaluate the larvicidal activity of a genetically engineered cyanobacterium, Anabaena PCC 7120#11, against five African Anopheles species in laboratory bioassays.

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Not Open Access | Actively induced antigen-specific CD8+ T cells by epitope-bearing parasite pre-infection but not prime/boost virus vector vaccination could ameliorate the course of Plasmodium yoelii blood-stage infection

September 13, 2012 - 04:40 -- Patrick Sampao
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Author(s): 
Takeshi Ono, Yoko Yamaguchi, Takemi Oguma, Eiji Takayama, Yasuhiro Takashima, Takushi Tadakuma, Yasushi Miyahira
Reference: 
Vaccine, Volume 30, Issue 44, 28 September 2012, Pages 6270-6278

MalariaWorldThis is the first study to implicate that the active induction of antigen-specific CD8+ T cells should be included in the development of a vaccine against MBS.

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Not Open Access | T cell control of malaria pathogenesis

August 20, 2012 - 11:26 -- Patrick Sampao
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Author(s): 
Philip J Spence, Jean Langhorne
Reference: 
Current Opinion in Immunology, Volume 24, Issue 4, August 2012, Pages 444-448

MalariaWorldRecent evidence demonstrates that it is the interplay between CD4+ and CD8+ T cells, and the regulation of their response, throughout infection that dictates immunity and the pathogenesis of malaria.

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Welcome to My Blog

August 6, 2012 - 15:11 -- Manas Sarkar
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Dear Collaborators / Colleagues / Friends & Follower

Myself Dr. Manas Sarkar, PhD from India. I've started this new blog in Malaria World. I'm a scientist & technologist trained in molecular & medical entomology, vector biology, ento-epidemiology, insecticide resistance & mode of action. I was the Dy. Asstt. Director of National Centre for Disease Control in India. Now, I took over the charge of General Manager (Technology) of EntoGenex Industries and also heading the operation in India.

My brief credentials are as follows:

Which is easier, to eradicate malaria or to find the Higgs Boson?

July 15, 2012 - 11:49 -- William Jobin
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Last week I was in Geneva, trying to understand the WHO fight against malaria, when - to my delight - the folks at CERN announced that they had found the Higgs Boson! In fact we were driving out near Geneva Airport, right over the Super Hadron Collider, when they made the announcement. But it made me wonder about WHO. Why was it easier for CERN to find the Boson than for WHO to suppress malaria?

Hunger games

July 2, 2012 - 21:41 -- Ricardo Ataide
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The day had been a hard one. Starting at 6am, it had been filled with hours in front of the computer trying to finish a grant proposal, finishing the review of a paper and looking at dozens of images of placentas... I got home after an hour of public transport in Sao Paulo (why in the hell I still believe that I should not contribute to this city's smog levels is beyond me!!) and my wife was performing some weird australian version of Yoga/Pilates that I'm sure no Indian teacher has ever mastered before. The usual "how was your day" does not work for us.

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