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Miles Markus's blog

Malaria and Hydrogen Peroxide

November 17, 2019 - 20:33 -- Miles Markus

In relation to some biological and epidemiological implications of the killing of Plasmodium vivax by hydrogen peroxide, discussed in a November 2019 publication (click on the first link below and, in turn, click on the "Free Download" link that comes up in a Tweet), see the comments in the MalariaWorld Newsletter by Pierre Lutgen concerning hydrogen peroxide. Find his blog via the second link provided below.

https://twitter.com/TrendsParasitol/status/1187787596317036544

Link to free P. vivax paper

October 30, 2019 - 19:32 -- Miles Markus

 

A link in the "Comment" on a new P. vivax publication listed in the MalariaWorld Newsletter this week does not appear to be "clickable". Therefore, the comment is reproduced below:

By taking the following route (if it works), this publication can be downloaded free for a limited time. Go via the link provided below. Then, in turn, click on the link in the tweet that should appear on your screen.

https://twitter.com/TrendsParasitol/status/1187787596317036544

 

Hypnozoites and relapse: theory partly wrong for the past 40 years

September 22, 2019 - 14:49 -- Miles Markus

 

Latest evidence for a non-hypnozoite (extra-hepatic), non-peripheral blood origin of Plasmodium vivax malarial recurrences:

https://doi.org/10.1016/j.pt.2019.08.009

 

Malaria: Writing Precisely

February 9, 2019 - 00:08 -- Miles Markus

 

Attention is drawn to the following three publications that are relevant to the preparation of manuscripts on malaria:

 

Markus, M.B. 2019. Plasmodium – Yet More Don’ts. Trends in Parasitology 35 (2): 101–102.

https://doi.org/10.1016/j.pt.2018.11.006

McFadden, G.I. 2019. Plasmodium – More Don’ts. Trends in Parasitology 35 (1): 4–6.

https://doi.org/10.1016/j.pt.2018.10.002

Why does vivax malaria recur?

January 24, 2019 - 23:14 -- Miles Markus

An article on vivax malarial recurrences was highlighted in the "Global Malaria News" section of last week's MalariaWorld Newsletter. Below (in the next paragraph) is a relevant explanation concerning the article (http://theconversation.com/why-does-malaria-recur-how-pieces-of-the-puzz...):

Significance of time to clinical recurrence in vivax malaria

October 12, 2018 - 10:55 -- Miles Markus

The amount of time that passes between a symptomatic vivax malarial episode and a subsequent recurrence has in the past often been regarded as an indication as to whether the recurrence is a relapse (hypnozoite origin) or a recrudescence (merozoite origin). It should be noted that in the light of new knowledge and understanding, the time factor is not a valid criterion. (Link to first paper). (Link to second paper).

Malaria elimination problem

September 13, 2018 - 23:36 -- Miles Markus

We talk about asymptomatic, submicroscopic plasmodial infections as potentially being a threat to the elimination of malaria. This is, of course, partly because such infections are not normally treated; especially not in rural endemic areas where laboratory facilities are limited. An aggravation of the situation is when parasitaemias are so low that they cannot be detected by molecular diagnosis (where available) either. But obstacles to elimination are probably even greater than has been realized.

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