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Copula geoadditive modelling of anaemia and malaria in young children in Kenya, Malawi, Tanzania and Uganda

November 10, 2020 - 13:46 -- Open Access
Roberts DJ, Zewotir T
J Health Popul Nutr. 2020 Nov 6;39(1):8

Anaemia and malaria are the leading causes of sub-Saharan African childhood morbidity and mortality. This study aimed to explore the complex relationship between anaemia and malaria in young children across the districts or counties of four contiguous sub-Saharan African countries, namely Kenya, Malawi, Tanzania and Uganda, while accounting for the effects of socio-economic, demographic and environmental factors. Geospatial maps were constructed to visualise the relationship between the two responses across the districts of the countries.

COVID-19 in malaria-endemic regions: potential consequences for malaria intervention coverage, morbidity, and mortality

September 29, 2020 - 13:28 -- Open Access
Teboh-Ewungkem MI, Ngwa GA
Lancet Infect Dis. 2020 Sep 21:S1473-3099(20)30763-5

COVID-19 has had a massive impact on the populations and economies of the world. As of Sept 9, 2020, the virus has infected more than 27 million people in 216 countries and territories worldwide, and the number of deaths is approaching a million.

Mortality from malaria in France, 2005 to 2014

September 15, 2020 - 15:01 -- Open Access
Kendjo E, Thellier M, Noël H, Jauréguiberry S, Septfons A, Mouri O, Gay F, Tantaoui I, Caumes E, Houzé S, Piarroux R
Euro Surveill. 2020 Sep;25(36)

Malaria is a notifiable disease in all European Union and European Economic Area countries except Belgium and France, where only autochthonous malaria is notifiable. Although morbidity caused by malaria has been assessed, little is known about mortality incidence.

Not Open Access | Genomic Approaches to Drug Resistance in Malaria

September 10, 2020 - 14:21 -- NOT Open Access
Rocamora F, Winzeler EA
Annu Rev Microbiol. 2020 Sep 8;74:761-786

Although the last two decades have seen a substantial decline in malaria incidence and mortality due to the use of insecticide-treated bed nets and artemisinin combination therapy, the threat of drug resistance is a constant obstacle to sustainable malaria control. Given that patients can die quickly from this disease, public health officials and doctors need to understand whether drug resistance exists in the parasite population, as well as how prevalent it is so they can make informed decisions about treatment.

Highlighting the burden of malarial infection and disease in the neonatal period: making sense of different concepts

September 1, 2020 - 09:59 -- Open Access
Abel Nhama, Rosauro Varo and Quique Bassat
Malaria Journal 2020 19:311, 28 August 2020

In malaria-endemic areas, the first year of life is indisputably considered one of the most vulnerable periods for malaria disease, and malaria-associated mortality in this age group is typically high, usually as a consequence of severe anaemia, among other possible complications.

Global prevalence and mortality of severe Plasmodium malariae infection: a systematic review and meta-analysis

August 4, 2020 - 15:51 -- Open Access
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni D. Milanez and Frederick R. Masangkay
Malaria Journal 2020 19:274, 31 July 2020

Severe complications among patients with Plasmodium malariae infection are rare. This is the first systematic review and meta-analysis demonstrating the global prevalence and mortality of severe P. malariae infection in humans.

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

March 9, 2020 - 13:57 -- Open Access
Djibrilla Issiaka, Amadou Barry, Tiangoua Traore, Boubacar Diarra, David Cook, Mohamed Keita, Issaka Sagara, Patrick Duffy, Michal Fried and Alassane Dicko
Malaria Journal 2020 19:103, 3 March 2020

Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the health system. This retrospective study assessed the impact of seasonal malaria chemoprevention (SMC) on hospitalizations and deaths of children under 5 years of age during the second year of implementation of SMC in the health district of Ouelessebougou in Mali.

Semi-field evaluation of the cumulative effects of a “Lethal House Lure” on malaria mosquito mortality

September 10, 2019 - 15:17 -- Open Access
Antoine M. G. Barreaux, Welbeck A. Oumbouke, Innocent Zran Tia, N’guessan Brou, Alphonsine A. Koffi, Raphaël N’guessan and Matthew B. Thomas
Malaria Journal 2019 18:298, 30 August 2019

There is growing interest in the potential to modify houses to target mosquitoes with insecticides or repellents as they search for human hosts. One version of this ‘Lethal House Lure’ approach is the In2Care® EaveTube, which consists of a section of polyvinyl chloride (PVC) pipe fitted into a closed eave, with an insert comprising electrostatic netting treated with insecticide powder placed inside the tube. Preliminary evidence suggests that when combined with screening of doors and windows, there is a reduction in entry of mosquitoes and an increase in mortality. However, the rate of overnight mortality remains unclear. The current study used a field enclosure built around experimental huts to investigate the mortality of cohorts of mosquitoes over multiple nights.

We thought we were down to 655.000 deaths in 2010, right?

February 3, 2012 - 10:46 -- Bart G.J. Knols

Year after year in December we're seeing the fruits of our collective efforts to combat malaria reflected in the 'World Malaria Report' series produced by the World Health Organisation. And in those reports, year after year, we saw progression in terms of falling numbers of deaths. But today we're confronted with a harsh reality - the figures that were presented to us were off. Way off.

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