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malaria prophylaxis

NOT Open Access | Hydroxychloroquine in COVID-19 Therapy: Protection Versus Proarrhythmia

July 27, 2020 - 12:13 -- NOT Open Access
Author(s): 
Stremmel C, Kellnar A, Massberg S, Kääb S
Reference: 
J Cardiovasc Pharmacol Ther. 2020 Jul 23:1074248420935740

In recent months, the new coronavirus SARS-CoV-2 has emerged as a worldwide threat with about 4.2 million confirmed cases and almost 300 000 deaths. Its major clinical presentation is characterized by respiratory symptoms ranging from mild cough to serve pneumonia with fever and potentially even death. Until today, there is no known medication to improve clinical symptoms or even prevent or fight the infection.

Impact of Doxycycline as Malaria Prophylaxis on Risk of Influenza-Like Illness among International Travelers

February 17, 2020 - 14:38 -- Open Access
Author(s): 
Lago K, Telu K, Yun H, et al.
Reference: 
Am J Trop Med Hyg. 2020 Feb 10

Travelers are often at risk for both influenza-like illness (ILI) and malaria. Doxycycline is active against pathogens causing ILI and is used for malaria prophylaxis. We evaluated the risk factors for ILI, and whether the choice of malaria prophylaxis was associated with ILI. TravMil is a prospective observational study enrolling subjects presenting to military travel clinics. Influenza-like illness was defined as subjective fever with either a sore throat or cough. Characteristics of trip and use of malaria prophylaxis were analyzed to determine association with development of ILI.

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