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Trends of malaria infection in pregnancy in Ghana over the past two decades: a review

January 12, 2022 - 23:40 -- Open Access
Joseph Osarfo, Gifty Dufie Ampofo and Harry Tagbor
Malaria Journal 2022 21:3, 4 January 2022

There has been a global decline in malaria transmission over the past decade. However, not much is known of the impact of this observation on the burden of malaria infection in pregnancy in endemic regions including Ghana. A narrative review was undertaken to help describe trends in malaria infection in pregnancy in Ghana. Among others, such information is important in showing any progress made in malaria in pregnancy control.

Trends and predictive factors for treatment failure following artemisinin-based combination therapy among children with uncomplicated malaria in Ghana: 2005-2018

December 23, 2021 - 10:02 -- Open Access
Abuaku B, Duah-Quashie NO, Quashie N, Gyasi A, Afriyie PO, Owusu-Antwi F, Ghansah A, Malm KL, Bart-Plange C, Koram KA
BMC Infect Dis. 2021 Dec 15;21(1):1255

Since the introduction of artemisinin-based combination therapy (ACT) in Ghana in 2005 there has been a surveillance system by the National Malaria Control Programme (NMCP) and the University of Ghana Noguchi Memorial Institute for Medical Research (UG-NMIMR) to monitor the therapeutic efficacy of ACTs for the treatment of uncomplicated malaria in the country. We report trends and determinants of failure following treatment of Ghanaian children with artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) combinations.

Insecticide-treated net (ITN) use, factors associated with non-use of ITNs, and occurrence of sand flies in three communities with reported cases of cutaneous leishmaniasis in Ghana

December 23, 2021 - 09:38 -- Open Access
Akuffo R, Wilson M, Sarfo B, Dako-Gyeke P, Adanu R, Anto F
PLoS One. 2021 Dec 16;16(12):e0261192

The insecticide treated bed net (ITN) has been proven for malaria control. Evidence from systematic review also suggests benefits of ITN roll out in reducing the incidence of cutaneous leishmaniasis (CL) and other vector borne diseases.

Guiding placement of health facilities using multiple malaria criteria and an interactive tool

December 17, 2021 - 21:36 -- Open Access
Kok Ben Toh, Justin Millar, Paul Psychas, Benjamin Abuaku, Collins Ahorlu, Samuel Oppong, Kwadwo Koram and Denis Valle
Malaria Journal 2021 20:455, 3 December 2021

Access to healthcare is important in controlling malaria burden and, as a result, distance or travel time to health facilities is often a significant predictor in modelling malaria prevalence. Adding new health facilities may reduce overall travel time to health facilities and may decrease malaria transmission. To help guide local decision-makers as they scale up community-based accessibility, the influence of the spatial allocation of new health facilities on malaria prevalence is evaluated in Bunkpurugu-Yunyoo district in northern Ghana. A location-allocation analysis is performed to find optimal locations of new health facilities by separately minimizing three district-wide objectives: malaria prevalence, malaria incidence, and average travel time to health facilities.

Assessing health-seeking behaviour and malaria prevention practices among communities in four districts of the Volta Region of Ghana

December 17, 2021 - 21:23 -- Open Access
Verner N. Orish, Raymond Saa-Eru Maalman, John Owusu Gyapong, et al.
Malaria Journal 2021 20:450, 27 November 2021

Malaria is a preventable disease that causes huge morbidity and mortality in malaria-endemic areas, especially among children and pregnant women. The malaria control programme focuses on the prevention of mosquito bites using insecticide-treated nets (ITNs) and mosquito aerosol sprays and coils, as well as prevention of severe disease among those infected through prompt and adequate treatment. The success of the malaria control programme in Ghana is dependent on the malaria prevention practices of people in the community. Therefore, this study evaluated the malaria prevention practices of participants in four districts of the Volta Region of Ghana.

The emergence of chloroquine-sensitive Plasmodium falciparum is influenced by selected communities in some parts of the Central Region of Ghana

December 15, 2021 - 21:17 -- Open Access
Kwame Kumi Asare, Justice Africa, Jennifer Mbata and Yeboah Kwaku Opoku
Malaria Journal 2021 20:447, 25 November 2021

The return of chloroquine-sensitive Plasmodium falciparum in sub-Saharan Africa countries offers the opportunity for the reintroduction of chloroquine (CQ) either in combination with other drugs or as a single therapy for the management of malaria. This study assesses the influence of individual study sites on the selection of CQ sensitive P. falciparum markers in the Central region of Ghana.

Evaluation of pilot implementation of seasonal malaria chemoprevention on morbidity in young children in Northern Sahelian Ghana

November 23, 2021 - 09:28 -- Open Access
Patrick O. Ansah, Nana A. Ansah, Abraham R. Oduro, et al.
Malaria Journal 2021 20:440, 18 November 2021

In Sahelian Africa, the risk of malaria increases with the arrival of the rains, particularly in young children. Following successful trials, the World Health Organization (WHO) recommended the use of seasonal malaria chemoprevention (SMC) in areas with seasonal peak in malaria cases. This study evaluated the pilot implementation of SMC in Northern Ghana.

Determinants of uptake of intermittent preventive treatment for malaria with sulfadoxine pyrimethamine in pregnancy: a cross-sectional analytical study in the Sekondi-Takoradi Metropolis of Ghana

October 20, 2021 - 19:55 -- Open Access
Anto F, Ayepah C, Awini E, Bimi L
Arch Public Health. 2021 Oct 14;79(1):177

Ghana malaria control programme recommends the uptake of five doses of sulfadoxine pyrimethamine (SP) during pregnancy following the review of the World Health Organization recommendations in 2012. The uptake of higher doses of SP since the implementation of the new policy in 2016, has been low across the country. The current study determined factors that can be improved to increase uptake of SP for intermittent preventive treatment of malaria in pregnancy (IPTp-SP).

Not Open Access | Ownership and Use of Insecticide-Treated Nets under Ghana's National Malaria Control Program: What are the correlates

October 16, 2021 - 20:17 -- NOT Open Access
Bawuah A, Ampaw S
Trop Med Int Health. 2021 Oct 12

Ghana’s National Malaria Control Program distributes free insecticide-treated nets (ITNs) as a malaria control measure. Some households with the ITN do not use it, however. This paper explores the socioeconomic and demographic determinants of ITN ownership and use among Ghanaian families.

Assessing health system factors affecting access and delivery of IPTp-SP and ITN to pregnant women attending ANC clinics in Ghana

October 16, 2021 - 20:02 -- Open Access
De-Gaulle VF, Magnussen P, Kamgno J, Mbacham W, Orish VN, Tagbor H
BMC Health Serv Res. 2021 Oct 6;21(1):1056

Malaria interventions including use of Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment (IPTp-SP) and distribution of Insecticide Treated Nets (ITNs) have been implemented through ante-natal clinic (ANC) services in Ghana. Yet, the high ANC attendance is not commensurate with the uptake of these interventions, with missed opportunities to deliver the interventions. This study sought to assess the health system factors affecting access and delivery of IPTp-SP and ITN as defined by the Ghana Malaria Policy Guideline to eligible pregnant women attending ANC clinic sessions.


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