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plasmodium parasites

Plasmobase: a comparative database of predicted domain architectures for Plasmodium genomes

June 13, 2017 - 16:42 -- Open Access
Author(s): 
Juliana Bernardes, Catherine Vaquero and Alessandra Carbone
Reference: 
Malaria Journal 2017 16:241, 7 June 2017

Plasmobase is a valuable new resource for domain annotation in Plasmodium genomes. Its graphical presentation of protein sequences, based on domain architectures, will hopefully be of interest for comparative genomic studies.

Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence

August 26, 2016 - 17:46 -- Open Access
Author(s): 
Nathan J. Dennison, Raúl G. Saraiva, Chris M. Cirimotich, Godfree Mlambo, Emmanuel F. Mongodin and George Dimopoulos
Reference: 
Malaria Journal 2016 15:425, 22 August 2016

Esp_Z is capable of inhibiting sporogonic development of Plasmodium in the presence of the mosquito’s native microbiota without affecting mosquito fitness.

NOT Open Access | In Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria Box Reveals Novel Compounds with Profound Activities against Theileria annulata Schizonts

May 25, 2016 - 17:49 -- NOT Open Access
Author(s): 
Isabel Hostettler, Joachim Müller, and Andrew Hemphill
Reference: 
Antimicrob. Agents Chemother. June 2016 vol. 60 no. 6 3301-3308

Intracellular schizonts of the apicomplexans Theileria annulata and Theileria parva immortalize bovine leukocytes and thereby cause fatal diseases.

Not Open Access | Antimalarial and cytotoxic properties of Chukrasia tabularis A. Juss and Turraea vogelii Hook F. Ex. Benth

March 22, 2016 - 17:43 -- NOT Open Access
Author(s): 
Omonike O. Ogbole, Yusuf A. Saka, Pius S. Fasinu, Adenike A. Fadare & Edith O. Ajaiyeoba
Reference: 
Parasitology Research April 2016, Volume 115, Issue 4, pp 1667-1674

Malaria, caused by plasmodium parasite, is at the moment the highest cause of morbidity and mortality in the tropics.

NOT Open Access | Sexual development in Plasmodium parasites: knowing when it's time to commit

August 31, 2015 - 15:40 -- NOT Open Access
Author(s): 
Gabrielle A. Josling & Manuel Llinas
Reference: 
Nature Reviews Microbiology 13, 573–587 (2015)

Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan parasites of the genus Plasmodium.

Antigen Export during Liver Infection of the Malaria Parasite Augments Protective Immunity

September 4, 2014 - 12:08 -- Open Access
Author(s): 
Georgina N. Montagna, Macarena Beigier-Bompadre, Martina Becker, Richard A. Kroczek, Stefan H. E. Kaufmann, and Kai Matuschewski
Reference: 
mBio.01321-14 29 July 2014 mBio vol. 5 no. 4 e01321-14

Protective immunity against preerythrocytic malaria parasite infection is difficult to achieve.

A Cysteine Protease Inhibitor of Plasmodium berghei Is Essential for Exo-erythrocytic Development

September 4, 2014 - 11:57 -- Open Access
Author(s): 
Christine Lehmann, Anna Heitmann, Volker Heussler, et al.
Reference: 
PLoS Pathog 10(8): e1004336

Plasmodium parasites express a potent inhibitor of cysteine proteases (ICP) throughout their life cycle.

Not Open Access | Antimitotic herbicides bind to an unidentified site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites

May 17, 2013 - 16:46 -- NOT Open Access
Author(s): 
Enda Dempsey, Miguel Prudêncio, Brian J. Fennell, Carina S. Gomes-Santos, James W. Barlow, Angus Bell
Reference: 
Molecular and Biochemical Parasitology, Volume 188, Issue 2, April 2013, Pages 116-127
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We conclude that the herbicides impair Plasmodium liver stage as well as blood stage development but that the location of their binding site on malarial parasite tubulin remains to be proven.

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