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vectorial capacity

Attrition, physical integrity and insecticidal activity of long-lasting insecticidal nets in sub-Saharan Africa and modelling of their impact on vectorial capacity

September 1, 2020 - 09:57 -- Open Access
Olivier Briet, Hannah Koenker, Tom Smith, et al.
Malaria Journal 2020 19:310, 28 August 2020

Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs are expected to last at least 3 years under normal use conditions, they can lose effectiveness because they fall out of use, are discarded, repurposed, physically damaged, or lose insecticidal activity. The contributions of these different interrelated factors to durability of nets and their protection against malaria have been unclear.

Not Open Access | Genetic engineering and bacterial pathogenesis against the vectorial capacity of mosquitoes

July 20, 2020 - 15:59 -- NOT Open Access
Qasim M, Xiao H, He K, Omar MAA, Liu F, Ahmed S, Li F
Microb Pathog. 2020 Jul 14:104391

Mosquitoes are the main vector of multiple diseases worldwide and transmit viral (malaria, chikungunya, encephalitis, yellow fever, as well as dengue fever), as well as bacterial diseases (tularemia). To manage the outbreak of mosquito populations, various management programs include the application of chemicals, followed by biological and genetic control.

Inference and prediction of malaria transmission dynamics using time series data

July 20, 2020 - 15:30 -- Open Access
Shi B, Lin S, Tan Q, Cao J, Zhou X, Xia S, Zhou XN, Liu J
Infect Dis Poverty. 2020 Jul 16;9(1):95

Disease surveillance systems are essential for effective disease intervention and control by monitoring disease prevalence as time series. To evaluate the severity of an epidemic, statistical methods are widely used to forecast the trend, seasonality, and the possible number of infections of a disease. However, most statistical methods are limited in revealing the underlying dynamics of disease transmission, which may be affected by various impact factors, such as environmental, meteorological, and physiological factors. In this study, we focus on investigating malaria transmission dynamics based on time series data.

GCE Special: Endectocides for controlling transmission of mosquito-borne diseases

May 27, 2013 - 19:40 -- Bart G.J. Knols
Massamba Sylla, Kevin C. Kobylinski, Brian D. Foy
MWJ 2013, 4, 5

The aim of this GCE project was to develop a control method that targets the most important variables of vectorial capacity (VC) and the basic reproductive number (Ro) so malaria parasite transmission would be maximally impacted, but that did so by targeting mosquitoes through human blood meals. This would a) target all malaria vectors around a community, regardless of when and where they bite, and b) ensure that the effector molecules directly entered the midgut of mosquitoes rather than needing to be efficiently applied in the environment and then efficiently penetrate the vectors’ cuticle.

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