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long-lasting insecticidal nets

NOT Open Access | Insecticide resistance and malaria control: A genetics-epidemiology modeling approach

July 13, 2020 - 15:49 -- NOT Open Access
Mohammed-Awel J, Iboi EA, Gumel AB
Math Biosci. 2020 Jul;325:108368

Malaria, a deadly infectious disease caused by the protozoan Plasmodium, remains a major public health menace affecting at least half the human race. Although the large-scale usage of insecticides-based control measures, notably long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), have led to a dramatic reduction of the burden of this global scourge between the period 2000 to 2015, the fact that the malaria vector (adult female Anopheles mosquito) has become resistant to all currently-available insecticides potentially makes the current laudable global effort to eradicate malaria by 2040 more challenging.

Comparing the durability of the long-lasting insecticidal nets DawaPlus® 2.0 and DuraNet© in northwest Democratic Republic of Congo

May 25, 2020 - 08:49 -- Open Access
Paul Mansiangi, Solange Umesumbu, Albert Kilian, et al.
Malaria Journal 2020 19:189, 24 May 2020

Anecdotal reports from DRC suggest that long-lasting insecticidal nets (LLIN) distributed through mass campaigns in DRC may not last the expected average three years. To provide the National Malaria Control Programme with evidence on physical and insecticidal durability of nets distributed during the 2016 mass campaign, two brands of LLIN, DawaPlus® 2.0 and DuraNet©, were monitored in neighbouring and similar health zones in Sud Ubangi and Mongala Provinces.

Monitoring the durability of the long-lasting insecticidal nets Olyset® and PermaNet® 2.0 in similar use environments in Zanzibar

May 25, 2020 - 08:41 -- Open Access
Khamis Ameir Haji, Bakari Omar Khatib, Albert Kilian, et al.
Malaria Journal 2020 19:187, 24 May 2020

Malaria transmission in Zanzibar has dramatically reduced in recent years but vector control interventions such as long-lasting insecticidal nets (LLIN) must continue to reach malaria elimination. To achieve this, the Zanzibar Malaria Elimination Programme needs actionable evidence of the durability of the LLIN brands distributed. This study compared physical and insecticidal durability of two LLIN brands: Olyset® and PermaNet© 2.0 in two similar districts on the islands of Unguja and Pemba.

Insufficient Ratio of Long-Lasting Insecticidal Nets to Household Members Limited Universal Usage in Western Kenya: A 2015 Cross-Sectional Study

April 23, 2020 - 10:06 -- Open Access
Coalson JE, Santos EM, Little AC, Anderson EJ, Stroupe N, Agawo M, Hayden M, Munga S, Ernst KC
Am J Trop Med Hyg. 2020 Apr 20

Universal “coverage” with long-lasting insecticidal nets (LLINs) is recommended for malaria control in endemic areas, but ownership does not ensure usage. We evaluated relationships between household-level ownership and individual-level usage in western Kenya in 2015. Low-prevalence highland (> 1,500 m) and highly endemic lowland (< 1,200 m) sites were surveyed from July to August 2015. Household members reported long-lasting insecticidal net ownership, use, and barriers to use.

Effect of long-lasting insecticidal nets with and without piperonyl butoxide on malaria indicators in Uganda (LLINEUP): a pragmatic, cluster-randomised trial embedded in a national LLIN distribution campaign

April 20, 2020 - 09:38 -- Open Access
Staedke SG, Gonahasa S, Donnelly MJ, et al.
Lancet. 2020 Apr 18;395(10232):1292-1303

Long-lasting insecticidal nets (LLINs) are the primary malaria prevention tool, but their effectiveness is threatened by pyrethroid resistance. We embedded a pragmatic cluster-randomised trial into Uganda’s national LLIN campaign to compare conventional LLINs with those containing piperonyl butoxide (PBO), a synergist that can partially restore pyrethroid susceptibility in mosquito vectors.

Long-lasting insecticidal nets retain bio-efficacy after 5 years of storage: implications for malaria control programmes

March 18, 2020 - 14:53 -- Open Access
Jeremiah J. Musa, Sarah J. Moore, Jason Moore, Emmanuel Mbuba, Edgar Mbeyela, Dickson Kobe, Johnson K. Swai and Olukayode G. Odufuwa
Malaria Journal 2020 19:110, 14 March 2020

Long-lasting insecticidal nets (LLINs) are the most sustainable and effective malaria control tool currently available. Global targets are for 80% of the population living in malaria endemic areas to have access to (own) and use a LLIN. However, current access to LLINs in endemic areas is 56% due to system inefficiencies and budget limitations. Thus, cost-effective approaches to maximize access to effective LLINs in endemic areas are required. This study evaluated whether LLINs that had been stored for 5 years under manufacturer’s recommended conditions may be optimally effective against Anopheles mosquitoes, to inform malaria control programmes and governments on the periods over which LLINs may be stored between distributions, in an effort to maximize use of available LLINs.

Physical integrity and survivorship of long-lasting insecticidal nets distributed to households of the same socio-cultural community in Benin, West Africa

February 10, 2020 - 16:05 -- Open Access
Idelphonse B. Ahogni, Albert S. Salako, Bruno Akinro, Arthur Sovi, Virgile Gnanguenon, Roseric Azondekon, Jean F. Dagnon, Pamela Akogbeto, Filémon Tokponon and Martin C. Akogbeto
Malaria Journal 2020 19:58, 4 February 2020

Long-lasting insecticidal nets (LLINs) are designed to survive and sustain their physical barrier for 3 years in household conditions. However, studies have shown that most of these nets are usually torn or no longer present in the households in less than 3 years. This study was initiated in Benin to compare the survivorship and physical integrity of seven types of LLINs in a same socio-geographic area.

Investigating the acceptability of non-mesh, long-lasting insecticidal nets amongst nomadic communities in Garissa County, Kenya using a prospective, longitudinal study design and cross-sectional household surveys

March 3, 2015 - 14:22 -- Open Access
Georgia R Gore-Langton, James Mungai, Richard Allan, et al.
Malaria Journal 2015, 14:52 (5 February 2015)

This study investigates the acceptability of non-mesh LLINs, specifically designed to suit nomadic, outdoor sleeping communities.

Evaluation of the coverage and effective use rate of long-lasting insecticidal nets after nation-wide scale up of their distribution in Benin

September 20, 2013 - 18:39 -- Open Access
Filémon T Tokponnon, Bruno Aholoukpe, Eric Y Denon, Virgile Gnanguenon, Alexis Bokossa, Raphael N'guessan, Mariam Oke, Dorothée Kinde Gazard and Martin C Akogbeto
Parasites & Vectors 2013, 6:265

The study was a cross-sectional household survey which utilized a stratified two-stage cluster sampling design.

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