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NOT Open Access | Malaria Epidemiology Along the Indian Districts Bordering Bhutan and Implications for Malaria Elimination in the Region

November 13, 2021 - 10:16 -- NOT Open Access
Gupta SK, Saroha P, Singh K, Saxena R, Barman K, Kumar A, Sharma A
Am J Trop Med Hyg. 2021 Nov 8:tpmd210513

It is important for malaria-endemic countries to address malaria control across international borders, and in particular to prioritize appropriate rapid diagnosis, treatment, and surveillance. Bhutan and India aim to achieve malaria elimination by 2023 and 2030, respectively. Malaria elimination along the Indo-Bhutan border is of common concern. We delineated malaria epidemiology along the border to provide a blueprint for focusing malaria control efforts in key foci within this region.

Community engagement approaches for malaria prevention, control and elimination: a scoping review protocol

October 16, 2021 - 13:04 -- Open Access
Awasthi KR, Jancey J, Clements ACA, Leavy JE
BMJ Open. 2021 Oct 5;11(10):e049812

Community engagement (CE) is important for malaria prevention, control and ultimately elimination. As the decline of malaria has plateaued over the last 5 years, strengthening CE approaches will be necessary to enhance health promotion practice and policy to drive malaria transmission down further. Countries have adopted a wide range of public health intervention approaches for malaria prevention and control that best suit their context. This review will examine the existing evidence on the various CE approaches adopted by malaria programmes across the world and their outcomes.

Quantifying malaria acquired during travel and its role in malaria elimination on Bioko Island

September 1, 2021 - 17:08 -- Open Access
Daniel T. Citron, Carlos A. Guerra, Guillermo A. García, Sean L. Wu, Katherine E. Battle, Harry S. Gibson and David L. Smith
Malaria Journal 2021 20:359, 30 August 2021

Malaria elimination is the goal for Bioko Island, Equatorial Guinea. Intensive interventions implemented since 2004 have reduced prevalence, but progress has stalled in recent years. A challenge for elimination has been malaria infections in residents acquired during travel to mainland Equatorial Guinea. The present article quantifies how off-island contributes to remaining malaria prevalence on Bioko Island, and investigates the potential role of a pre-erythrocytic vaccine in making further progress towards elimination.

Investment case for malaria elimination in South Africa: a financing model for resource mobilization to accelerate regional malaria elimination

August 18, 2021 - 16:30 -- Open Access
Joseph Njau, Sheetal P. Silal, Aparna Kollipara, Katie Fox, Ryleen Balawanth, Anthony Yuen, Lisa J. White, Mandisi Moya, Yogan Pillay and Devanand Moonasar
Malaria Journal 2021 20:344, 16 August 2021

Malaria continues to be a public health problem in South Africa. While the disease is mainly confined to three of the nine provinces, most local transmissions occur because of importation of cases from neighbouring countries. The government of South Africa has reiterated its commitment to eliminate malaria within its borders. To support the achievement of this goal, this study presents a cost–benefit analysis of malaria elimination in South Africa through simulating different scenarios aimed at achieving malaria elimination within a 10-year period.

Evaluation of the effectiveness and cost effectiveness of a Community-delivered Integrated Malaria Elimination (CIME) model in Myanmar: protocol for an open stepped-wedge cluster-randomised controlled trial

August 17, 2021 - 15:17 -- Open Access
Oo WH, Thi A, Htike W, Agius PA, Cutts JC, Win KM, Yi Linn NY, Than WP, Hkawng GN, Thu KM, Oo MC, O'Flaherty K, Kearney E, Scott N, Phyu PP, Htet AT, Myint O, Lwin Yee L, Thant ZP, Mon A, Htike S, Hnin TP, Fowkes FJI
BMJ Open. 2021 Aug 13;11(8):e050400

In the Greater Mekong Subregion, community health workers, known as malaria volunteers, have played a key role in reducing malaria in the control phase, providing essential malaria services in areas with limited formal healthcare. However, the motivation and social role of malaria volunteers, and testing rates, have declined with decreasing malaria burden and reorientation of malaria programmes from control to elimination. Provision of additional interventions for common health concerns could help sustain the effectiveness of volunteers and maintain malaria testing rates required for malaria elimination accreditation by the WHO.

Genetic surveillance in the Greater Mekong subregion and South Asia to support malaria control and elimination

August 10, 2021 - 18:10 -- Open Access
Jacob CG, Thuy-Nhien N, Miotto O, et al.
Elife. 2021 Aug 10;10:e62997

National Malaria Control Programmes (NMCPs) currently make limited use of parasite genetic data. We have developed GenRe-Mekong, a platform for genetic surveillance of malaria in the Greater Mekong Subregion (GMS) that enables NMCPs to implement large-scale surveillance projects by integrating simple sample collection procedures in routine public health procedures.

Inference of malaria reproduction numbers in three elimination settings by combining temporal data and distance metrics

July 20, 2021 - 14:01 -- Open Access
Routledge I, Unwin HJT, Bhatt S
Sci Rep. 2021 Jul 14;11(1):14495

Individual-level geographic information about malaria cases, such as the GPS coordinates of residence or health facility, is often collected as part of surveillance in near-elimination settings, but could be more effectively utilised to infer transmission dynamics, in conjunction with additional information such as symptom onset time and genetic distance. However, in the absence of data about the flow of parasites between populations, the spatial scale of malaria transmission is often not clear. As a result, it is important to understand the impact of varying assumptions about the spatial scale of transmission on key metrics of malaria transmission, such as reproduction numbers. We developed a method which allows the flexible integration of distance metrics (such as Euclidian distance, genetic distance or accessibility matrices) with temporal information into a single inference framework to infer malaria reproduction numbers.

Analysing human population movement data for malaria control and elimination

July 7, 2021 - 08:00 -- Open Access
Greta Tam, Benjamin J. Cowling and Richard J. Maude
Malaria Journal 2021 20:294, 30 June 2021

Human population movement poses a major obstacle to malaria control and elimination. With recent technological advances, a wide variety of data sources and analytical methods have been used to quantify human population movement (HPM) relevant to control and elimination of malaria.

Implementation and success factors from Thailand’s 1-3-7 surveillance strategy for malaria elimination

April 28, 2021 - 15:52 -- Open Access
Cheewanan Lertpiriyasuwat, Prayuth Sudathip, Preecha Prempree, et al.
Malaria Journal 2021 20:201, 27 April 2021

Thailand’s National Malaria Elimination Strategy 2017–2026 introduced the 1-3-7 strategy as a robust surveillance and response approach for elimination that would prioritize timely, evidence-based action. Under this strategy, cases are reported within 1 day, cases are investigated within 3 days, and foci are investigated and responded to within 7 days, building on Thailand’s long history of conducting case investigation since the 1980s. However, the hallmark of the 1-3-7 strategy is timeliness, with strict deadlines for reporting and response to accelerate elimination.

From 30 million to zero malaria cases in China: lessons learned for China-Africa collaboration in malaria elimination

April 22, 2021 - 08:27 -- Open Access
Chen JH, Fen J, Zhou XN
Infect Dis Poverty. 2021 Apr 20;10(1):51

Malaria was once one of the most serious public health problems in China, with more than 30 million malaria cases annually before 1949. However, the disease burden has sharply declined and the epidemic areas has shrunken after the implementation of an integrated malaria control and elimination strategy, especially since 2000.


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