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nets

CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

August 18, 2020 - 14:57 -- Open Access
Author(s): 
Rodrigues DAS, Prestes EB, Bozza MT, et al.
Reference: 
PLoS Pathog. 2020 Aug 14;16(8):e1008230

Neutrophil extracellular traps (NETs) evolved as a unique effector mechanism contributing to resistance against infection that can also promote tissue damage in inflammatory conditions. Malaria infection can trigger NET release, but the mechanisms and consequences of NET formation in this context remain poorly characterized.

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