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Comprehensive competency assessment of malaria microscopists and laboratory diagnostic service capacity in districts stratified for malaria elimination in Ethiopia

June 29, 2020 - 16:12 -- Open Access
Nega D, Abebe A, Abera A, Gidey B, G/Tsadik A, Tasew G
PLoS One. 2020 Jun 25; 15(6):e0235151

Federal Ministry of Health (FMoH) Ethiopia achieved significant declines in malaria mortality and incidence and has recently launched malaria elimination in selected low transmission settings. Successful malaria elimination calls for rapid and accurate diagnosis of cases so that the patients can promptly be treated before the occurrence of transmission. Therefore, this study assessed the competency of malaria microscopists using panal slides, and laboratory service availability and readiness in terms of supplies and equipments in malaria elimination targeted districts in Ethiopia.

Exploring the impact of cattle on human exposure to malaria mosquitoes in the Arba Minch area district of southwest Ethiopia

June 26, 2020 - 15:18 -- Open Access
Zeru MA, Shibru S, Massebo F
Parasit Vectors. 2020 Jun 22;13(1):322

The success of indoor interventions that target mosquitoes for malaria control is partially dependent on early evening and outdoor biting behaviours of mosquito vectors. In southwest Ethiopia, people and cattle live in proximity, which calls to investigate whether the presence of cattle increase or decrease bites from malaria mosquito vectors. This study assessed both host-seeking and overnight activity of malaria mosquito vectors given the presence or absence of cattle in Chano Mille village, Arba Minch district, Ethiopia.

Disseminating clinical study results to trial participants in Ethiopia: insights and lessons learned

June 9, 2020 - 16:13 -- Open Access
Tamiru S. Degaga, Sophie Weston, Kamala Thriemer, et al.
Malaria Journal 2020 19:205, 8 June 2020

International regulatory authorities and funders require that research be disseminated promptly and appropriately to all involved stakeholders. However, following completion of clinical trials participants often either do not receive any feedback or materials provided are not appropriate for the context.

Genetic diversity and genotype multiplicity of Plasmodium falciparum infection in patients with uncomplicated malaria in Chewaka district, Ethiopia

June 9, 2020 - 16:07 -- Open Access
Abdulhakim Abamecha, Hassan El-Abid, Alemseged Abdissa, et al.
Malaria Journal 2020 19:203, 8 June 2020

Genetic diversity in Plasmodium falciparum poses a major threat to malaria control and elimination interventions. Characterization of the genetic diversity of P. falciparum strains can be used to assess intensity of parasite transmission and identify potential deficiencies in malaria control programmes, which provides vital information to evaluating malaria elimination efforts. This study investigated the P. falciparum genetic diversity and genotype multiplicity of infection in parasite isolates from cases with uncomplicated P. falciparum malaria in Southwest Ethiopia.

Performance of malaria microscopy external quality assessment and networking among health facilities in west Amhara region, Ethiopia

May 21, 2020 - 06:35 -- Open Access
Tegegne B, Ejigu K, Alemu G, Fetene Y, Endaylalu K, Melese M
BMC Infect Dis. 2020 May 19; 20(1):355

Microscopic examination of peripheral blood smear produces reliable results both about the malaria infection status and level of parasitemia. However, test results are affected by skill of the laboratory personnel, workload, condition of microscopes and quality of laboratory supplies. Therefore, continuous monitoring of the performance of laboratories is of pivotal importance in order to make timely correction.

NOT Open Access | Case Report: Primaquine Failure for Radical Cure of Plasmodium vivax Malaria in Gambella, Ethiopia

May 13, 2020 - 14:45 -- NOT Open Access
Teklehaimanot A, Teklehaimanot H, Girmay A, Woyessa A
Am J Trop Med Hyg. 2020 May 11

Failures of primaquine for the treatment of relapsed Plasmodium vivax malaria is a serious challenge to malaria elimination in Ethiopia, where P. vivax accounts for up to 40% of malaria infections. We report here occurrence of a total of 15 episodes of primaquine treatment failure for radical cure in three historical P. vivax malaria patients from Gambella, Ethiopia, during 8–16 months of follow-up in 1985–1987.

Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia

May 12, 2020 - 16:42 -- Open Access
Solomon Yared, Araya Gebressielasie, Lambodhar Damodaran, Victoria Bonnell, Karen Lopez, Daniel Janies and Tamar E. Carter
Malaria Journal 2020 19:180, 12 May 2020

The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The recent report of Anopheles stephensi in eastern Ethiopia has raised the necessity to understand the insecticide resistance status of the vector in the region to better inform vector-based interventions. The aim of this study was to evaluate insecticide resistance in An. stephensi in eastern Ethiopia using two approaches: (1) World Health Organization (WHO) bioassay tests in An. stephensi; and (2) genetic analysis of insecticide resistance genes in An. stephensi in eastern Ethiopia.

Evaluation of human-baited double net trap and human-odour-baited CDC light trap for outdoor host-seeking malaria vector surveillance in Kenya and Ethiopia

May 12, 2020 - 16:31 -- Open Access
Teshome Degefa, Delenasaw Yewhalaw, Guofa Zhou, Harrysone Atieli, Andrew K. Githeko and Guiyun Yan
Malaria Journal 2020 19:174, 7 May 2020

Surveillance of outdoor host-seeking malaria vectors is crucial to monitor changes in vector biting behaviour and evaluate the impact of vector control interventions. Human landing catch (HLC) has been considered the most reliable and gold standard surveillance method to estimate human-biting rates. However, it is labour-intensive, and its use is facing an increasing ethical concern due to potential risk of exposure to infectious mosquito bites. Thus, alternative methods are required. This study was conducted to evaluate the performance of human-odour-baited CDC light trap (HBLT) and human-baited double net trap (HDNT) for outdoor host-seeking malaria vector surveillance in Kenya and Ethiopia.

Trend of declining bed net utilization among pregnant women in Ethiopia: new data from the Arba Minch Health and Demographic Surveillance System, 2010–2016

April 13, 2020 - 13:42 -- Open Access
Teklemariam Gultie, Gistane Ayele, Alazar Baharu, et al.
Malaria Journal 2020 19:142, 8 April 2020

Bed net utilization is one of the important methods of malaria prevention. Malaria during pregnancy is one of the fatal diseases which mostly leads to the death of the mother and the fetus. Some of the complications of malaria during pregnancy are: intrauterine growth restrictions, intrauterine fetal death, and stillbirth. The main challenge of malaria treatment is that most of the anti-malarial drugs are not safe to use during pregnancy. The use of bed net is the most effective method of prevention of malaria during pregnancy. There is a paucity of information on bed net utilization among pregnant women in the study setting. Hence, this study aims to assess the trends of bed net utilization among pregnant women in Arba Minch Health and Demography Surveillance Site (HDSS), Southern Ethiopia.

Trend of malaria prevalence in Wolkite health center: an implication towards the elimination of malaria in Ethiopia by 2030

March 19, 2020 - 08:54 -- Open Access
Absra Solomon, Daniel Kahase and Mihret Alemayehu
Malaria Journal 2020 19: 112, 16 March 2020

Malaria is one of the main public health challenges in Ethiopia that hinder the productivity and development of the country. In 2018, Ethiopia is on track to minimize the incidence of malaria by 40% as per its 2020 malaria reduction strategy. Currently, Ethiopia is working to eliminate malaria in 2030 by extending the 2020 strategy. Hence, this study aimed to analyze the trend of malaria prevalence in Wolkite health center, Gurage zone, Southern Central Ethiopia from 2015 to 2018.


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