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pyrethroid resistant

Transfluthrin eave-positioned targeted insecticide (EPTI) reduces human landing rate (HLR) of pyrethroid resistant and susceptible malaria vectors in a semi-field simulated peridomestic space

September 1, 2021 - 16:39 -- Open Access
Mgeni M. Tambwe, Sarah Moore, Lorenz Hofer, Ummi A. Kibondo and Adam Saddler
Malaria Journal 2021 20:357, 30 August 2021

Volatile pyrethroids (VPs) are proven to reduce human–vector contact for mosquito vectors. With increasing resistance to pyrethroids in mosquitoes, the efficacy of VPs, such as transfluthrin, may be compromised. Therefore, experiments were conducted to determine if the efficacy of transfluthrin eave-positioned targeted insecticide (EPTI) depends on the resistance status of malaria vectors.

Which indoor residual spraying insecticide best complements standard pyrethroid long-lasting insecticidal nets for improved control of pyrethroid resistant malaria vectors

February 2, 2021 - 16:15 -- Open Access
Syme T, Fongnikin A, Todjinou D, Govoetchan R, Gbegbo M, Rowland M, Akogbeto M, Ngufor C
PLoS One. 2021 Jan 28;16(1):e0245804

Where resources are available, non-pyrethroid IRS can be deployed to complement standard pyrethroid LLINs with the aim of achieving improved vector control and managing insecticide resistance. The impact of the combination may however depend on the type of IRS insecticide deployed. Studies comparing combinations of pyrethroid LLINs with different types of non-pyrethroid IRS products will be necessary for decision making.

Attrition, physical integrity and insecticidal activity of long-lasting insecticidal nets in sub-Saharan Africa and modelling of their impact on vectorial capacity

September 1, 2020 - 09:57 -- Open Access
Olivier Briet, Hannah Koenker, Tom Smith, et al.
Malaria Journal 2020 19:310, 28 August 2020

Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs are expected to last at least 3 years under normal use conditions, they can lose effectiveness because they fall out of use, are discarded, repurposed, physically damaged, or lose insecticidal activity. The contributions of these different interrelated factors to durability of nets and their protection against malaria have been unclear.

Genomic Variant Analyses in Pyrethroid Resistant and Susceptible Malaria Vector, Anopheles sinensis

May 20, 2020 - 10:29 -- Open Access
Chang X, Zhong D, Wang X, Bonizzoni M, Li Y, Zhou G, Cui L, Wei X, Yan G
G3 (Bethesda). 2020 May 18:g3.401279.2020

Anopheles sinensis is a major malaria vector in Southeast Asia. Resistance to pyrethroid insecticides in this species has impeded malaria control in the region. Previous studies found that An. sinensis populations from Yunnan Province, China were highly resistant to deltamethrin and did not carry mutations in the voltage-gated sodium channel gene that cause knockdown resistance.

Olyset Duo® (a Pyriproxyfen and Permethrin Mixture Net): An Experimental Hut Trial against Pyrethroid Resistant Anopheles gambiae and Culex quinquefasciatus in Southern Benin

April 16, 2014 - 18:30 -- Open Access
Corine Ngufor, Raphael N’Guessan, Josias Fagbohoun, Abibatou Odjo, David Malone, Martin Akogbeto, Mark Rowland
PLoS ONE 9(4): e93603

Mixing pyrethroid and pyriproxyfen on a LN shows potential for malaria control and management of pyrethroid resistant vectors by preventing further selection of pyrethroid resistant phenotypes.

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