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NOT Open Access | Insecticide resistance and malaria control: A genetics-epidemiology modeling approach

July 13, 2020 - 15:49 -- NOT Open Access
Author(s): 
Mohammed-Awel J, Iboi EA, Gumel AB
Reference: 
Math Biosci. 2020 Jul;325:108368

Malaria, a deadly infectious disease caused by the protozoan Plasmodium, remains a major public health menace affecting at least half the human race. Although the large-scale usage of insecticides-based control measures, notably long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), have led to a dramatic reduction of the burden of this global scourge between the period 2000 to 2015, the fact that the malaria vector (adult female Anopheles mosquito) has become resistant to all currently-available insecticides potentially makes the current laudable global effort to eradicate malaria by 2040 more challenging.

Biological larviciding against malaria vector mosquitoes with Bacillus thuringiensis israelensis (Bti) - Long term observations and assessment of repeatability during an additional intervention year of a large-scale field trial in rural Burkina Faso

January 1, 2020 - 15:56 -- Open Access
Author(s): 
Dambach P, Winkler V, Bärnighausen T, Traoré I, Ouedraogo S, Sié A, Sauerborn R, Becker N, Louis VR
Reference: 
Glob Health Action. 2020 Dec 31;13(1):1829828

The first line of malaria vector control to date mainly relies on the use of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS). For integrated vector management, targeting the vector larvae with biological larvicides such as Bacillus thuringiensis israelensis (Bti) can be an effective additional mainstay. This study presents data from the second intervention year of a large-scale trial on biological larviciding with Bti that was carried out in 127 rural villages and a semi-urban town in Burkina Faso.

Should pyrethroids be banned for Indoor Residual Spraying (IRS)?

May 20, 2010 - 11:41 -- Bart G.J. Knols
Tags: 

Today a new forum topic was launched by Drs Derek Charlwood and Erling Pedersen from DBL in Copenhagen. They argue that pyrethroids should no longer be used for indoor residual spraying and be reserved for use on bednets. What's your opinion?

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