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plasmodium yoelli

Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis

May 25, 2011 - 07:57 -- Kabogo Ndegwa
Author(s): 
Valeelat O. Okeola, Oluwatosin A. Adaramoye, Chiaka M. Nneji, Catherine O. Falade, E. Olatunde Farombi and Olusegun G. Ademowo
Reference: 
Parasitology Research, Volume 108, Number 6, 1507-1512

The antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (MENS) were investigated against established malaria infection in vivo using Swiss albino mice.

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Synthesis of 9-anilinoacridine triazines as new class of hybrid antimalarial agents.

November 18, 2009 - 13:00 -- Patrick Sampao
Author(s): 
Ashok Kumar, Kumkum Srivastava, S. Raja Kumar, S.K. Puri, Prem M.S. Chauhan
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 19, Issue 24, 15 December 2009, Pages 6996-6999, doi:10.1016/j.bmcl.2009.10.010

There is challenge and urgency to synthesize cost-effective chemotherapeutic agents for treatment of malarianext term after the widespread development of resistance to CQ. In the present study, we synthesized a new series of hybrid 9-anilinoacridine triazines using the cheap chemicals 6,9-dichloro-2-methoxy acridine and cyanuric chloride.

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