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Inaugural Article: Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine

November 11, 2009 - 10:16 -- Ingeborg van Schayk
Juliana Martha Sá, Olivia Twu, Karen Hayton, Sahily Reyes, Michael P. Fay, Pascal Ringwald, and Thomas E. Wellems
PNAS November 10, 2009 vol. 106 no. 45 18883-18889

Increasing use of AQ in Africa poses the threat of a selective sweep of highly AQ-resistant, CQ-resistant parasites with pfcrt and pfmdr1 mutations that are as advantaged and persistent as in South America.


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