The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 11110 malaria professionals are enjoying the free benefits of MalariaWorld today

cluster randomized trial

Prevalence and associated risk factors of asymptomatic malaria and anaemia among school-aged children in Dara Mallo and Uba Debretsehay districts: results from baseline cluster randomized trial

October 27, 2021 - 14:00 -- Open Access
Author(s): 
Zerihun Zerdo, Hilde Bastiaens, Sibyl Anthierens, Fekadu Massebo, Matewos Masne, Gelila Biresaw, Misgun Shewangizaw, Abayneh Tunje, Yilma Chisha, Tsegaye Yohannes and Jean-Pierre Van Geertruyden
Reference: 
Malaria Journal 2021 20:400, 13 October 2021

Despite the growing evidence that malaria and anaemia are two interlinked health problems of school-aged children (SAC) in developing countries, there is scarce information about malaria among SAC in Ethiopia. Moreover, anaemia-related studies were more concentrated in easily accessible areas. This study aimed to assess the prevalence of malaria and anaemia and corresponding risk factors among SAC in Dara Mallo and Uba Debretshay districts, in hard to reach areas, so as to inform appropriate integrated interventions for both diseases.

On the cost-effectiveness of insecticide-treated wall liner and indoor residual spraying as additions to insecticide treated bed nets to prevent malaria: findings from cluster randomized trials in Tanzania

September 23, 2021 - 09:11 -- Open Access
Author(s): 
Mpangala KR, Halasa-Rappel YA, Shepard DS, et al.
Reference: 
BMC Public Health. 2021 Sep 14;21(1):1666

Despite widespread use of long-lasting insecticidal nets (LLINs) and other tools, malaria caused 409,000 deaths worldwide in 2019. While indoor residual spraying (IRS) is an effective supplement, IRS is moderately expensive and logistically challenging. In endemic areas, IRS requires yearly application just before the main rainy season and potential interim reapplications. A new technology, insecticide-treated wall liner (ITWL), might overcome these challenges.

Analysis of contamination in cluster randomized trials of malaria interventions

September 15, 2021 - 11:26 -- Open Access
Author(s): 
Multerer L, Glass TR, Vanobberghen F, Smith T
Reference: 
Trials. 2021 Sep 10;22(1):613

In cluster randomized trials (CRTs) of interventions against malaria, mosquito movement between households ultimately leads to contamination between intervention and control arms, unless they are separated by wide buffer zones.

High efficacy of microbial larvicides for malaria vectors control in the city of Yaounde Cameroon following a cluster randomized trial

August 25, 2021 - 17:15 -- Open Access
Author(s): 
Antonio-Nkondjio C, Doumbe-Belisse P, Wondji CS, et al.
Reference: 
Sci Rep. 2021 Aug 24;11(1):17101

The rapid expansion of insecticide resistance and outdoor malaria transmission are affecting the efficacy of current malaria control measures. In urban settings, where malaria transmission is focal and breeding habitats are few, fixed and findable, the addition of anti-larval control measures could be efficient for malaria vector control. But field evidences for this approach remains scarce.

Effect of group versus individual antenatal care on uptake of intermittent prophylactic treatment of malaria in pregnancy and related malaria outcomes in Nigeria and Kenya: analysis of data from a pragmatic cluster randomized trial

February 3, 2020 - 17:17 -- Open Access
Author(s): 
Lisa Noguchi, Lindsay Grenier, Oniyire Adetiloye, et al.
Reference: 
Malaria Journal 2020 19:51, 29 January 2020

Every year, malaria in pregnancy contributes to approximately 20% of stillbirths in sub-Saharan Africa and 10,000 maternal deaths globally. Most eligible pregnant women do not receive the minimum three recommended doses of intermittent preventive treatment with Sulfadoxine–pyrimethamine (IPTp-SP). The objective of this analysis was to determine whether women randomized to group antenatal care (G-ANC) versus standard antenatal care (ANC) differed in IPTp uptake and insecticide-treated nets (ITN) use.

Subscribe to RSS - cluster randomized trial