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nucleic acid

WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three

March 31, 2020 - 15:32 -- Open Access
Author(s): 
Jane A. Cunningham, Rebecca M. Thomson, Jaya Shrivastava, et al.
Reference: 
Malaria Journal 2020 19:129, 30 March 2020

The World Health Organization (WHO) recommends parasite-based diagnosis of malaria. In recent years, there has been surge in the use of various kinds of nucleic-acid amplification based tests (NAATs) for detection and identification of Plasmodium spp. to support clinical care in high-resource settings and clinical and epidemiological research worldwide. However, these tests are not without challenges, including lack (or limited use) of standards and lack of reproducibility, due in part to variation in protocols amongst laboratories. Therefore, there is a need for rigorous quality control, including a robust external quality assessment (EQA) scheme targeted towards malaria NAATs. To this effect, the WHO Global Malaria Programme worked with the UK National External Quality Assessment Scheme (UK NEQAS) Parasitology and with technical experts to launch a global NAAT EQA scheme in January 2017.

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