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Children with Plasmodium vivax infection previously observed in Namibia, were Duffy negative and carried a c.136G > A mutation

August 25, 2021 - 16:53 -- Open Access
Haiyambo DH, Aleksenko L, Mumbengegwi D, Bock R, Uusiku P, Malleret B, Rénia L, Quaye IK
BMC Infect Dis. 2021 Aug 21;21(1):856

In a previous study, using a molecular approach, we reported the presence of P. vivax in Namibia. Here, we have extended our investigation to the Duffy antigen genetic profile of individuals of the same cohort with and without Plasmodium infections.

Malaria risk factors in northern Namibia: The importance of occupation, age and mobility in characterizing high-risk populations

June 30, 2021 - 09:29 -- Open Access
Smith JL, Mumbengegwi D, Haindongo E, Cueto C, Roberts KW, Gosling R, Uusiku P, Kleinschmidt I, Bennett A, Sturrock HJ
PLoS One. 2021 Jun 25;16(6):e0252690

In areas of low and unstable transmission, malaria cases occur in populations with lower access to malaria services and interventions, and in groups with specific malaria risk exposures often away from the household. In support of the Namibian National Vector Borne Disease Program's drive to better target interventions based upon risk, we implemented a health facility-based case control study aimed to identify risk factors for symptomatic malaria in Zambezi Region, northern Namibia.

Community acceptance of reactive focal mass drug administration and reactive focal vector control using indoor residual spraying, a mixed‐methods study in Zambezi region, Namibia

March 24, 2021 - 14:44 -- Open Access
Kathryn W. Roberts, Cara Smith Gueye, Michelle S. Hsiang, et al.
Malaria Journal 2021 20:162, 22 March 2021

In Namibia, as in many malaria elimination settings, reactive case detection (RACD), or malaria testing and treatment around index cases, is a standard intervention. Reactive focal mass drug administration (rfMDA), or treatment without testing, and reactive focal vector control (RAVC) in the form of indoor residual spraying, are alternative or adjunctive interventions, but there are limited data regarding their community acceptability.

Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial

April 27, 2020 - 14:00 -- Open Access
Hsiang MS, Ntuku H, Gosling R, et al.
Lancet. 2020 Apr 25;395(10233):1361-1373

In low malaria-endemic settings, screening and treatment of individuals in close proximity to index cases, also known as reactive case detection (RACD), is practised for surveillance and response. However, other approaches could be more effective for reducing transmission. We aimed to evaluate the effectiveness of reactive focal mass drug administration (rfMDA) and reactive focal vector control (RAVC) in the low malaria-endemic setting of Zambezi (Namibia).

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