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eurasian siskins

Host Transcriptional Responses to High- and Low-Virulent Avian Malaria Parasites

June 1, 2020 - 16:28 -- Open Access
Videvall E, Palinauskas V, Valkiūnas G, Hellgren O
Am Nat. 2020 Jun; 195(6):1070-1084

The transcriptional response of hosts to genetically similar pathogens can vary substantially, with important implications for disease severity and host fitness. A low pathogen load can theoretically elicit both high and low host responses, as the outcome depends on both the effectiveness of the host at suppressing the pathogen and the ability of the pathogen to evade the immune system. Here, we investigate the transcriptional response of Eurasian siskins (Spinus spinus) to two closely related lineages of the malaria parasite Plasmodium relictum.

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