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Recent Molecular Assessment of Plasmodium vivax and Plasmodium falciparum Asymptomatic Infections in Botswana

May 5, 2021 - 11:52 -- Open Access
Motshoge T, Haiyambo DH, Quaye IK, et al.
Am J Trop Med Hyg. 2021 May 3:tpmd210083

In 2016, we reported the presence of Plasmodium vivax in Botswana through active case detection. A real-time PCR was used during a similar study in 10 districts to assess changes in the P. vivax prevalence. We assessed 1,614 children (2-13 years of age) for hemoglobin (Hb; g/dL) and Plasmodium parasites. The median age of all participants was 5.0 years (25th percentile, 3 years; 75th percentile, 8 years).

Spatial Anopheles arabiensis (Diptera: Culicidae) insecticide resistance patterns across malaria-endemic regions of Botswana

November 24, 2020 - 13:44 -- Open Access
Mmabaledi Buxton, Ryan J. Wasserman and Casper Nyamukondiwa
Malaria Journal 2020 19:415, 19 November 2020

Since the advent of the Green Revolution, pesticides have played an important role in the global management of invertebrate pests including vector mosquitoes. Despite optimal efficacy, insects often display insensitivity to synthetic insecticides owing to prolonged exposure that may select for resistance development. Such insecticide insensitivity may regress national and regional coordination in mosquito vector management and indeed malaria control. In Botswana, prolonged use of synthetic insecticides against malaria vectors have been practiced without monitoring of targeted mosquito species susceptibility status.

Vector control for malaria elimination in Botswana: progress, gaps and opportunities

August 27, 2020 - 08:11 -- Open Access
Tefo Kesaobaka Kgoroebutswe, Ntebaleng Makate, Ulrike Fillinger, Mandla Mpho, Godira Segoea, Peter Onyango Sangoro, Clifford Maina Mutero, Emmanuel Chanda, Davies Ntebela, Mpho Mogopa, Tjantilili Mosweunyane and Theresia Estomih Nkya
Malaria Journal 2020 19:301, 26 August 2020

Botswana has in the recent past 10 years made tremendous progress in the control of malaria and this informed re-orientation from malaria control to malaria elimination by the year 2020. This progress is attributed to improved case management, and scale-up of key vector control interventions; indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs). However, insecticide resistance, outdoor biting and resting, and predisposing human behaviour, such as staying outdoors or sleeping outdoors without the use of protective measures, pose a challenge to the realization of the full impact of LLINs and IRS.

NOT Open Access | ast and current biological factors affecting malaria in the low transmission setting of Botswana: A review

July 16, 2020 - 07:58 -- NOT Open Access
Bango ZA, Tawe L, Muthoga CW, Paganotti GM
Infect Genet Evol. 2020 Jul 12:104458

Malaria continues to be one of the top infectious agents contributing to morbidity and mortality in sub-Saharan Africa. Annually, Botswana accounts only for a small proportion of cases (<<1%). Despite significantly reduced incidence rate, the country still experiences sporadic outbreaks that hamper the goal of malaria elimination. This review evaluated previous and current biological factors that impact malaria in Botswana, specifically focussing on the vectors, the parasite and the host. This was accomplished via a literature review evaluating these variables in Botswana.

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