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Tenebenal: a meta-diamide with potential for use as a novel mode of action insecticide for public health

November 11, 2020 - 14:17 -- Open Access
Rosemary Susan Lees, Pauline Ambrose, Jessica Williams, John Morgan, Giorgio Praulins, Victoria A. Ingham, Chris T. Williams, Rhiannon Agnes Ellis Logan, Hanafy M. Ismail and David Malone
Malaria Journal 2020 19:398, 10 November 2020

There is an urgent need for insecticides with novel modes of action against mosquito vectors. Broflanilide is a meta-diamide, discovered and named Tenebenal™ by Mitsui Chemicals Agro, Inc., which has been identified as a candidate insecticide for use in public health products.

A cohort study to identify risk factors for Plasmodium falciparum infection in Burkinabe children: implications for other high burden high impact countries

October 20, 2020 - 16:24 -- Open Access
Jean Baptiste Yaro, Alphonse Ouedraogo, Anne L. Wilson, et al.
Malaria Journal 2020 19:371, 16 October 2020

Progress in controlling malaria has stalled in recent years. Today the malaria burden is increasingly concentrated in a few countries, including Burkina Faso, where malaria is not declining. A cohort study was conducted to identify risk factors for malaria infection in children in southwest Burkina Faso, an area with high insecticide-treated net (ITN) coverage and insecticide-resistant vectors.

Infection of highly insecticide-resistant malaria vector Anopheles coluzzii with entomopathogenic bacteria Chromobacterium violaceum reduces its survival, blood feeding propensity and fecundity

October 6, 2020 - 12:45 -- Open Access
Edounou Jacques Gnambani, Etienne Bilgo, Adama Sanou, Roch K. Dabiré and Abdoulaye Diabaté
Malaria Journal 2020 19:352, 2 October 2020

This is now a concern that malaria eradication will not be achieved without the introduction of novel control tools. Microbiological control might be able to make a greater contribution to vector control in the future. The interactions between bacteria and mosquito make mosquito microbiota really promising from a disease control perspective. Here, the impact of Chromobacterium violaceum infections, isolated from both larvae and adult of wild-caught Anopheles gambiae sensu lato mosquitoes in Burkina Faso, was evaluated on mosquito survival, blood feeding and fecundity.

Patterns of pesticide usage in agriculture in rural Tanzania call for integrating agricultural and public health practices in managing insecticide-resistance in malaria vectors

July 20, 2020 - 15:13 -- Open Access
Nancy S. Matowo, Marcel Tanner, Givemore Munhenga, Salum A. Mapua, Marceline Finda, Jürg Utzinger, Vera Ngowi and Fredros O. Okumu
Malaria Journal 2020 19:257, 16 July 2020

Unrestricted use of pesticides in agriculture is likely to increase insecticide resistance in mosquito vectors. Unfortunately, strategies for managing insecticide resistance in agriculture and public health sectors lack integration. This study explored the types and usage of agricultural pesticides, and awareness and management practices among retailers and farmers in Ulanga and Kilombero districts in south-eastern Tanzania, where Anopheles mosquitoes are resistant to pyrethroids.

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